| Name | glutathione S transferase |
|---|---|
| Synonyms | GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2… |
| Name | methyl bromide |
|---|---|
| CAS | bromomethane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 7979958 | Hallier E, Schroder KR, Asmuth K, Dommermuth A, Aust B, Goergens HW: Metabolism of dichloromethane (methylene to in human erythrocytes: influence of polymorphism of glutathione transferase theta (GST T1-1). Arch Toxicol. 1994;68(7):423-7. The formation of from dichloromethane is influenced by the polymorphism of glutathione-S-transferase (GST) Theta, in the same way as the metabolism of methyl bromide, methyl methyl iodide and ethylene oxide. |
81(1,1,1,1) | Details |
| 1733043 | Davenport CJ, Ali SF, Miller FJ, Lipe GW, Morgan KT, Bonnefoi MS: Effect of methyl bromide on regional brain glutathione-S-transferases, monoamines, and amino acids in F344 rats. Toxicol Appl Pharmacol. 1992 Jan;112(1):120-7. |
12(0,0,2,2) | Details |
| 8704864 | Garnier R, Rambourg-Schepens MO, Muller A, Hallier E: Glutathione transferase activity and formation of macromolecular adducts in two cases of acute methyl bromide poisoning. Occup Environ Med. 1996 Mar;53(3):211-15. To examine the influence of the polymorphism of glutathione-S-transferase theta (GSTT1) on the neurotoxicity of methyl bromide. |
6(0,0,1,1) | Details |
| 11474733 | Buchwald AL, Muller M: Late confirmation of acute methyl bromide poisoning using adduct testing. Vet Hum Toxicol. 2001 Aug;43(4):208-11. Additionally, genotyping of the glutathione-S-transferase TI enzyme in erthyrocytes from this case characterized a predisposition to the effects of methyl bromide. |
6(0,0,1,1) | Details |
| 8494496 | Hallier E, Langhof T, Dannappel D, Leutbecher M, Schroder K, Goergens HW, Muller A, Bolt HM: Polymorphism of conjugation of methyl bromide, ethylene oxide and dichloromethane in human blood: influence on the induction of sister chromatid exchanges (SCE) in lymphocytes. Arch Toxicol. 1993;67(3):173-8. A hitherto unknown glutathione-S-transferase in human erythrocytes displays polymorphism: three quarters of the population ("conjugators") possess, whereas one quarter ("non-conjugators") lack this specific activity. |
2(0,0,0,2) | Details |
| 1575765 | Schroder KR, Hallier E, Peter H, Bolt HM: Dissociation of a new glutathione S-transferase activity in human erythrocytes. Biochem Pharmacol. 1992 Apr 15;43(8):1671-4. |
1(0,0,0,1) | Details |
| 12415426 | Muller M, Bunger J, Voss M, Westphal G, Ruhnau P, Hallier E: Phenotyping of human glutathione S-transferase hGSTT1-1: a comparison of two ex vivo routine procedures. Arch Toxicol. 2002 Nov;76(11):634-42. Epub 2002 Aug 9. We have developed a routine ex vivo photometric phenotyping procedure based on the determination of release rates from the hGSTT1-1-catalyzed conjugation of the substrate methyl bromide in EDTA blood samples under standard conditions (1,000 ppm methyl bromide, 10 min incubation). |
1(0,0,0,1) | Details |