| Name | Acetylcholinesterase |
|---|---|
| Synonyms | ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant… |
| Name | biphenyl |
|---|---|
| CAS | 1,1′-biphenyl |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19285534 | Orhan I, Senol FS, Gulpinar AR, Kartal M, Sekeroglu N, Deveci M, Kan Y, Sener B: Acetylcholinesterase inhibitory and antioxidant properties of Cyclotrichium niveum, Thymus praecox subsp. caucasicus var. caucasicus, Echinacea purpurea and E. pallida. Food Chem Toxicol. 2009 Jun;47(6):1304-10. Epub 2009 Mar 12. |
4(0,0,0,4) | Details |
| 17888667 | Kavitha CV, Gaonkar SL, Narendra Sharath Chandra JN, Sadashiva CT, Rangappa KS: Synthesis and screening for acetylcholinesterase inhibitor activity of some novel 2-butyl-1,3-diaza-spiro [4,4] non-1-en-4-ones: derivatives of irbesartan key intermediate. Bioorg Med Chem. 2007 Dec 1;15(23):7391-8. Epub 2007 Aug 19. |
4(0,0,0,4) | Details |
| 19343477 | Lee YK, Yuk DY, Kim TI, Kim YH, Kim KT, Kim KH, Lee BJ, Nam SY, Hong JT: Protective effect of the extract of Magnolia officinalis and 4-O-methylhonokiol on -induced memory impairment and the inhibition of acetylcholinesterase activity. J Nat Med. 2009 Jul;63(3):274-82. Epub 2009 Apr 4. |
2(0,0,0,2) | Details |
| 19384728 | Orhan I, Ozcelik B, Aslan S, Kartal M, Karaoglu T, Sener B, Terzioglu S, Iqbal Choudhary M: In vitro biological activity screening of Lycopodium complanatum L. ssp. chamaecyparissus (A. Nat Prod Res. 2009;23(6):514-26. Anticholinesterase effect of the extracts was tested against both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) at concentrations of 0.2 and 1 mg mL (-1) using microplate-reader assay based on Ellman method. |
2(0,0,0,2) | Details |
| 19788497 | Tazzeo T, Worek F, Janssen Lj: The oxidase inhibitor diphenyleneiodonium is also a potent inhibitor of cholinesterases and the internal Ca (2+) pump. Br J Pharmacol. 2009 Oct;158(3):790-6. Epub 2009 Sep 25. Direct biochemical assays confirmed that DPI was a potent inhibitor of acetylcholinesterase and butyrylcholinesterase (IC (50) approximately 8 x 10 (-6) M and 6 x 10 (-7) M, respectively), following a readily reversible, mixed non-competitive type of inhibition. |
1(0,0,0,1) | Details |
| 18504554 | Puntel GO, Gubert P, Peres GL, Bresolin L, Rocha JB, Pereira ME, Carratu VS, Soares FA: Antioxidant properties of oxime 3-(phenylhydrazono) . Arch Toxicol. 2008 Oct;82(10):755-62. Epub 2008 May 27. Oximes are a class of compounds normally used to reverse the acetylcholinesterase (AChE) inhibition caused by organophosphates (OPs). |
1(0,0,0,1) | Details |
| 18976927 | Morini G, Comini M, Rivara M, Rivara S, Bordi F, Plazzi PV, Flammini L, Saccani F, Bertoni S, Ballabeni V, Barocelli E, Mor M: Synthesis and structure-activity relationships for biphenyl H3 receptor antagonists with moderate anti-cholinesterase activity. Bioorg Med Chem. 2008 Dec 1;16(23):9911-24. Epub 2008 Oct 17. The combination of antagonism at H (3) receptors and inhibition of acetylcholinesterase has been recently proposed as an approach to devise putative new therapeutic agents for cognitive diseases. |
1(0,0,0,1) | Details |
| 19500634 | Pereira DM, Faria J, Gaspar L, Valentao P, de Pinho PG, Andrade PB: Boerhaavia diffusa: metabolite profiling of a medicinal plant from Nyctaginaceae. Food Chem Toxicol. 2009 Aug;47(8):2142-9. Epub 2009 Jun 13. Moreover, activity against acetylcholinesterase, an enzyme with a well-known role in several physio-pathological processes, was assayed. |
1(0,0,0,1) | Details |
| 18950608 | Puntel GO, de Carvalho NR, Gubert P, Palma AS, Dalla Corte CL, Avila DS, Pereira ME, Carratu VS, Bresolin L, da Rocha JB, Soares FA: Butane-2,3-dionethiosemicarbazone: an oxime with antioxidant properties. Chem Biol Interact. 2009 Jan 27;177(2):153-60. Epub 2008 Oct 4. Oximes are compounds generally used to reverse the acetylcholinesterase (AChE) inhibition caused by organophosphates (OPs). |
1(0,0,0,1) | Details |