| Name | cytochrome P450 1B1 |
|---|---|
| Synonyms | CP1B; CYP1B1; CYPIB 1; CYPIB1; Cytochrome P450 1B1; GLC3A; Cytochrome P450 1B1s |
| Name | biphenyl |
|---|---|
| CAS | 1,1′-biphenyl |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19563207 | Shimada T, Tanaka K, Takenaka S, Foroozesh MK, Murayama N, Yamazaki H, Guengerich FP, Komori M: Reverse type I binding spectra of human cytochrome P450 1B1 induced by stilbene, pyrene, naphthalene, phenanthrene, and biphenyl derivatives that inhibit catalytic activity: a structure-function relationship study. Chem Res Toxicol. 2009 Jul;22(7):1325-33. |
31(0,1,1,1) | Details |
| 18178546 | Silkworth JB, Carlson EA, McCulloch C, Illouz K, Goodwin S, Sutter TR: Toxicogenomic analysis of gender, chemical, and dose effects in livers of TCDD- or aroclor 1254-exposed rats using a multifactor linear model. Toxicol Sci. 2008 Apr;102(2):291-309. Epub 2008 Jan 3. The relative potency of dioxins and polychlorinated biphenyl mixtures, such as Aroclor 1254, is often estimated using the internationally endorsed toxic equivalency (TEQ) approach. The known aryl hydrocarbon receptor (AHR) battery genes (Cyp1a1, Cyp1a2, Cyp1b1, Aldh3a1), and novel genes, responded in a TEQ dose-dependent manner in both genders. |
1(0,0,0,1) | Details |
| 19548353 | Shimada T, Murajama N, Tanaka K, Takenaka S, Imai Y, Hopkins NE, Foroozesh MK, Alworth WL, Yamazaki H, Guengerich FP, Komori M: Interaction of polycyclic aromatic hydrocarbons with human cytochrome P450 1B1 in inhibiting catalytic activity. Chem Res Toxicol. 2008 Dec;21(12):2313-23. Most of the chemicals examined were direct inhibitors of P450 1B1 except for 4-(1-propynyl) biphenyl, a mechanism-based inhibitor. |
1(0,0,0,1) | Details |