| Name | transferase |
|---|---|
| Synonyms | 4' phosphopantetheinyl transferase; 4' phosphopantetheinyl transferase; AASD PPT; AASDHPPT; AASDPPT; Alpha aminoadipic semialdehyde dehydrogenase phosphopantetheinyl transferase; Aminoadipate semialdehyde dehydrogenase phosphopantetheinyl transferase; CGI 80… |
| Name | biphenyl |
|---|---|
| CAS | 1,1′-biphenyl |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18215353 | Wang H, Ping J, Peng RX, Yue J, Xia XY, Li QX, Kong R, Hong JY: Changes of multiple biotransformation phase I and phase II enzyme activities in human fetal adrenals during fetal development. Acta Pharmacol Sin. 2008 Feb;29(2):231-8. The diphosphoglucuronyl transferase activities, which were measured using p-hydroxy-biphenyl and 7--4-methylcoumarin as substrates, were 9% and 3%, respectively, of those in the fetal livers. |
31(0,1,1,1) | Details |
| 18284184 | Gelain A, Barlocco D, Kwon BM, Jeong TS, Im KR, Legnani L, Toma L: Biphenyl versus phenylpyridazine derivatives: the role of the heterocycle in a series of acyl-CoA:cholesterol acyl transferase inhibitors. J Med Chem. 2008 Mar 13;51(5):1474-7. Epub 2008 Feb 20. |
31(0,1,1,1) | Details |
| 19147759 | Ichite N, Chougule MB, Jackson T, Fulzele SV, Safe S, Singh M: Enhancement of docetaxel anticancer activity by a novel diindolylmethane compound in human non-small cell lung cancer. Clin Cancer Res. 2009 Jan 15;15(2):543-52. PURPOSE: This study was conducted to examine the cytotoxic effects of a peroxisome proliferator-activated receptor gamma (PPARgamma) agonist, 1,1-bis (3'-indolyl)-1-(p-biphenyl) (DIM-C-pPhC (6) H (5)), alone and in combination with docetaxel in vitro in A549 lung cancer cells and in vivo in nude mice bearing A549 orthotopic lung tumors. Apoptosis was evaluated in A549 cells by terminal deoxynucleotidyl transferase-mediated nick end labeling assay and measurement of cleaved poly (ADP- polymerase level. |
2(0,0,0,2) | Details |
| 17892458 | Liu Y, Chen L, He X, Fan L, Yang G, Chen X, Lin X, DU L, Li Z, Ye H, Mao Y, Zhao X, Wei Y: Enhancement of therapeutic effectiveness by combining liposomal honokiol with cisplatin in ovarian carcinoma. Int J Gynecol Cancer. 2008 Jul-Aug;18(4):652-9. Epub 2007 Sep 24. Assessment of microvessel density and apoptosis index by CD31 and terminal deoxynucleotidyl transferase-mediated nick end labeling immunohistochemistry respectively suggested that the antitumor activity of H-PEGL is mediated by angiogenesis inhibition and introduction of apoptosis. |
1(0,0,0,1) | Details |
| 18946183 | Yun JW, Shin ES, Cho SY, Kim SH, Kim CW, Lee TR, Kim BH: The effects of BADGE and on the time-course response of adiponectin and lipid oxidative enzymes in high fat diet-fed C57BL/6J mice: correlation with reduced adiposity and steatosis. Exp Anim. 2008 Oct;57(5):461-9. ACC phosphorylation and palmitoyl-transferase-1 (CPT1) activity have been shown to be rate controlling factors in fatty acid oxidation. |
1(0,0,0,1) | Details |
| 18281560 | Hahm ER, Arlotti JA, Marynowski SW, Singh SV: Honokiol, a constituent of oriental medicinal herb magnolia officinalis, inhibits growth of PC-3 xenografts in vivo in association with apoptosis induction. Clin Cancer Res. 2008 Feb 15;14(4):1248-57. Tumor sections from control and honokiol-treated mice were examined for apoptotic bodies (terminal deoxyribonucleotidyl transferase-mediated nick end labeling assay), proliferation index (proliferating cell nuclear antigen staining), and neovascularization (CD31 staining). |
1(0,0,0,1) | Details |
| 18788898 | Verreault J, Maisonneuve F, Dietz R, Sonne C, Letcher RJ: Comparative hepatic activity of xenobiotic-metabolizing enzymes and concentrations of organohalogens and their hydroxylated analogues in captive Greenland sledge dogs (Canis familiaris). Environ Toxicol Chem. 2009 Jan;28(1):162-72. When the exposed and control dogs were combined, the summed (sigma) plasma concentrations of OH-polychlorinated biphenyl (PCB) congeners were predicted by plasma sigmaPCB concentrations and EROD activity (p < or = 0.04), whereas hydroxylase, EH, and UDPGT activities were not significant predictors of these concentrations. |
0(0,0,0,0) | Details |