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Renna JM, Strang CE, Amthor FR, Keyser KT: Strychnine, but not PMBA, inhibits neuronal nicotinic acetylcholine receptors expressed by rabbit retinal ganglion cells. Vis Neurosci. 2007 Jul-Aug;24(4):503-11.
We tested the effects of low micromolar concentrations of strychnine and 3-[2'-phosphonomethyl [1,1'-biphenyl]-3-yl] alanine (PMBA), a specific glycine receptor blocker (Saitoh et al., 1994; Hosie et al., 1999) on the activation of both alpha7 nAChRs on retinal ganglion cells and on ganglion cell responses to a light flash. |
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