| 18834876 |
Deguchi M, Kishino J, Hattori M, Furue Y, Yamamoto M, Mochizuki I, Iguchi M, Hirano Y, Hojou K, Nagira M, Nishitani Y, Okazaki K, Yasui K, Arimura A: Suppression of immunoglobulin production by a novel dihydroorotate dehydrogenase inhibitor, S-2678. Eur J Pharmacol. 2008 Dec 28;601(1-3):163-70. Epub 2008 Sep 20.
We discovered a novel dihydroorotate dehydrogenase (DHO-DH) inhibitor, S-2678 ([2-fluoro-2',5'-dimethyl-4'-[6-(3-methyl-2-butenyloxy) pyridin-3-yl] biphenyl-4-yl]-(3-methyl-2-butenyl) amine). |
32(0,1,1,2) |
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| 18672895 |
Walse B, Dufe VT, Svensson B, Fritzson I, Dahlberg L, Khairoullina A, Wellmar U, Al-Karadaghi S: The structures of human dihydroorotate dehydrogenase with and without inhibitor reveal conformational flexibility in the inhibitor and substrate binding sites. Biochemistry. 2008 Aug 26;47(34):8929-36. Epub 2008 Aug 2.
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6(0,0,0,6) |
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