| Name | alanine aminotransferase |
|---|---|
| Synonyms | AAT1; AAT1; GPT; ALT 1; ALT1; Alanine aminotransferase; Alanine aminotransferase 1; GPT 1… |
| Name | biphenyl |
|---|---|
| CAS | 1,1′-biphenyl |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19280152 | Chen YH, Lin FY, Liu PL, Huang YT, Chiu JH, Chang YC, Man KM, Hong CY, Ho YY, Lai MT: Antioxidative and hepatoprotective effects of magnolol on -induced liver damage in rats. Arch Pharm Res. 2009 Feb;32(2):221-8. Epub 2009 Mar 13. After evaluating the changes of several biochemical parameters in serum, the levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) were elevated by (500 mg/kg) intraperitoneal administration (8 and 24 h) and reduced by treatment with magnolol (0.5 h after administration; 0.01, 0.1, and 1 mug/kg). |
1(0,0,0,1) | Details |
| 19898808 | Kim MH, Lee J, Yoo DS, Lee YG, Byeon SE, Hong EK, Cho JY: Protective effect of stress-induced liver damage by saponin fraction from Codonopsis lanceolata. Arch Pharm Res. 2009 Oct;32(10):1441-6. Epub 2009 Nov 8. Cl-SF clearly decreased the up-regulated levels of serum - transaminase and glutamate-pyruvate-transaminase induced by water-immersed stress conditions. |
1(0,0,0,1) | Details |
| 19219550 | Yao XM, Zhao J, Li Y, Li Y: Effects of bicyclol on liver regeneration after partial hepatectomy in rats. Dig Dis Sci. 2009 Apr;54(4):774-81. Epub 2009 Feb 14. At 6, 24, and 48 h after resection, samples were collected for the measurement of serum alanine aminotransferase (ALT), total (TBil), hepatic glycogen, malondialdehyde (MDA), superoxide dismutase (SOD), and glutathione (GSH). |
1(0,0,0,1) | Details |
| 19429327 | Shen X, Tang Y, Yang R, Yu L, Fang T, Duan JA: The protective effect of Zizyphus jujube fruit on carbon tetrachloride-induced hepatic injury in mice by anti-oxidative activities. J Ethnopharmacol. 2009 Apr 21;122(3):555-60. Epub 2009 Feb 7. MATERIALS AND METHODS: The alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were detected as biomarker in blood of hepatic injury. |
1(0,0,0,1) | Details |
| 18949895 | Krishnakumar NM, Latha PG, Suja SR, Shine VJ, Shyamal S, Anuja GI, Sini S, Pradeep S, Shikha P, Unni PK, Rajasekharan S: Hepatoprotective effect of Hibiscus hispidissimus Griffith, ethanolic extract in and CCl4 induced hepatotoxicity in Wistar rats. Indian J Exp Biol. 2008 Sep;46(9):653-9. The results showed that significant hepatoprotective effects were obtained against liver damage induced by PCM and CCl4 as evidenced by decreased levels of serum enzymes, transaminase (SGOT), glutamate pyruvate transaminase (SGPT), serum alkaline phosphatase (SAKP), serum (SB) and an almost normal histological architecture of the liver of the treated groups compared to the toxin controls. |
1(0,0,0,1) | Details |
| 19966836 | Dai L, Ji H, Kong XW, Zhang YH: Antifibrotic effects of ZK14, a novel -donating biphenyldicarboxylate derivative, on rat HSC-T6 cells and CCl4-induced hepatic fibrosis. Acta Pharmacol Sin. 2010 Jan;31(1):27-34. Epub 2009 Dec 7. Levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), (HA), type III collagen (PCIII), and (NO) were assessed, and liver samples were stained with hematoxylin-eosin. |
1(0,0,0,1) | Details |
| 18435715 | Hou Y, Li L, Wei H, Wu L, Tong Y, Wu S, Liu G: Protection by bicyclol derivatives against -induced acute liver failure in mice and its active mechanism. Liver Int. 2008 Nov;28(9):1226-35. Epub 2008 Apr 23. METHODS: At first, 10 derivatives of bicyclol were tested in male KunMing strain mice injected with CCl (4), or d-galactosamine plus lipopolysaccharide (LPS), serum alanine aminotransferase (ALT) and mortality rate were determined. |
1(0,0,0,1) | Details |
| 18392951 | Bao XQ, Liu GT: Bicyclol: a novel antihepatitis drug with hepatic heat shock protein 27/70-inducing activity and cytoprotective effects in mice. Cell Stress Chaperones. 2008 Sep;13(3):347-55. Epub 2008 Apr 8. The prior administration of bicyclol markedly suppressed AP-induced liver injury as indicated by the reduction in the elevation of serum alanine aminotransferase and aspartate aminotransferase, in liver necrosis, in the release of cytochrome c and apoptosis-inducing factor from mitochondria, as well as in hepatic deoxyribonucleic acid fragmentation in mice. |
1(0,0,0,1) | Details |
| 19204334 | Deem SL, Norton TM, Mitchell M, Segars A, Alleman AR, Cray C, Poppenga RH, Dodd M, Karesh WB: Comparison of blood values in foraging, nesting, and stranded loggerhead turtles (Caretta caretta) along the coast of Georgia, USA. J Wildl Dis. 2009 Jan;45(1):41-56. Differences in plasma biochemistry values included the highest kinase, and CO (2) values in stranded turtles; the highest and values in foraging turtles; and the highest and triglyceride values, and lowest alanine aminotransferase, in nesting turtles. Plasma organochlorine and polychlorinated biphenyl levels were below their limits of quantification in the 39 foraging, 11 nesting, and three stranded turtles tested. |
1(0,0,0,1) | Details |
| 18371952 | Zhao J, Chen H, Li Y: Protective effect of bicyclol on acute -induced liver injury in mice. Eur J Pharmacol. 2008 May 31;586(1-3):322-31. Epub 2008 Feb 29. As a result, bicyclol pretreatment significantly protected against acute -induced liver injury as evidenced by the decrease of elevated serum alanine aminotransferase and hepatic triglyceride, and the attenuation of histopathological changes in mice. |
1(0,0,0,1) | Details |
| 19371623 | Yin HQ, Kim YC, Chung YS, Kim YC, Shin YK, Lee BH: Honokiol reverses alcoholic fatty liver by inhibiting the maturation of sterol regulatory element binding protein-1c and the expression of its downstream lipogenesis genes. Toxicol Appl Pharmacol. 2009 Apr 1;236(1):124-30. Epub 2009 Jan 24. Male Wistar rats fed with a standard Lieber-DeCarli diet for 4 weeks exhibited increased hepatic triglyceride and decreased hepatic levels, with concomitantly increased serum alanine aminotransferase and TNF-alpha levels. |
1(0,0,0,1) | Details |