| 19307114 |
Moss N, Choi Y, Cogan D, Flegg A, Kahrs A, Loke P, Meyn O, Nagaraja R, Napier S, Parker A, Thomas Peterson J, Ramsden P, Sarko C, Skow D, Tomlinson J, Tye H, Whitaker M: A new class of 5-HT2B antagonists possesses favorable potency, selectivity, and rat pharmacokinetic properties. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2206-10. Epub 2009 Mar 9.
This Letter describes our investigation of a biphenyl benzimidazole class of compounds that resulted in 5-HT (2B) antagonists possessing the above attributes. |
34(0,1,1,4) |
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