| Name | NMDA receptors (protein family or complex) |
|---|---|
| Synonyms | Glutamate [NMDA] receptor; Glutamate [NMDA] receptors; N methyl D aspartate receptor; N methyl D aspartate receptors; NMDA receptor; NMDA receptors |
| Name | biphenyl |
|---|---|
| CAS | 1,1′-biphenyl |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 20350588 | Hackler EA, Byun NE, Jones CK, Williams JM, Baheza R, Sengupta S, Grier MD, Avison M, Conn PJ, Gore JC: Selective potentiation of the metabotropic glutamate receptor subtype 2 blocks phencyclidine-induced hyperlocomotion and brain activation. Neuroscience. 2010 Mar 27. Indeed, biphenyl indanone-A (BINA), an allosteric potentiator of mGluR2, is effective in experimental models of psychosis, blocking phencyclidine (PCP)-induced hyperlocomotion and prepulse inhibition deficits in mice. In this study, we administered the NMDA receptor antagonist PCP (5.6 mg/kg i.p.) to rats, an established animal model predictive of schizophrenia. |
1(0,0,0,1) | Details |
| 19832997 | Lin YR, Chen HH, Lin YC, Ko CH, Chan MH: Antinociceptive actions of honokiol and magnolol on glutamatergic and inflammatory pain. J Biomed Sci. 2009 Oct 16;16:94. Furthermore, their different potency on inhibition of nociception provoked by NMDA receptor and mGluR5 activation should be considered. |
1(0,0,0,1) | Details |
| 19022367 | Ndountse LT, Chan HM: Role of N-methyl-D-aspartate receptors in polychlorinated biphenyl mediated neurotoxicity. Toxicol Lett. 2009 Jan 10;184(1):50-5. Epub 2008 Oct 28. |
32(0,1,1,2) | Details |
| 17728388 | Hellier JL, Grosshans DR, Coultrap SJ, Jones JP, Dobelis P, Browning MD, Staley KJ: NMDA receptor trafficking at recurrent synapses stabilizes the state of the CA3 network. J Neurophysiol. 2007 Nov;98(5):2818-26. Epub 2007 Aug 29. |
6(0,0,0,6) | Details |
| 20092573 | Reed BT, Sullivan SJ, Tsai G, Coyle JT, Esguerra M, Miller RF: The transporter GlyT1 controls receptor coagonist occupancy in the mouse retina. Eur J Neurosci. 2009 Dec;30(12):2308-17. Epub 2009 Dec 10. We examined the role of GlyT1, the high-affinity transporter, in the mouse retina with an emphasis on the role of as a coagonist of (NMDA) receptors. Capillary electrophoresis was used to separate and quantitatively measure release from isolated retina preparations; pharmacologically blocking GlyT1 with N-[3-([1,1-biphenyl]-4-yloxy)-3-(4-fluorophenyl) propyl]- in the WT retina generated a significantly larger accumulation of into the bathing environment when compared with the GlyT1 (-/+) retinas. |
5(0,0,0,5) | Details |
| 18930747 | Hellier JL, White A, Williams PA, Edward Dudek F, Staley KJ: NMDA receptor-mediated long-term alterations in epileptiform activity in experimental chronic epilepsy. Neuropharmacology. 2009 Feb;56(2):414-21. Epub 2008 Oct 7. |
3(0,0,0,3) | Details |
| 17959203 | Linderholm KR, Andersson A, Olsson S, Olsson E, Snodgrass R, Engberg G, Erhardt S: Activation of rat ventral tegmental area neurons by endogenous a pharmacological analysis. Neuropharmacology. 2007 Dec;53(8):918-24. Epub 2007 Sep 20. (KYNA) is an endogenous NMDA receptor antagonist as well as a blocker of the alpha7* nicotinic receptor and mounting evidence suggests that the compound participates in the pathophysiology of schizophrenia. |
2(0,0,0,2) | Details |