Name | Lipoxygenase (protein family or complex) |
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Synonyms | arachidonate lipoxygenase; arachidonate lipoxygenases; lipoxygenase; lipoxygenases |
Name | biphenyl |
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CAS | 1,1′-biphenyl |
PubMed | Abstract | RScore(About this table) | |
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18536755 | Kim HJ, Kim DK, Kim H, Koh JY, Kim KM, Noh MS, Lee S, Kim S, Park SH, Kim JJ, Kim SY, Lee CH: Involvement of the BLT2 receptor in the itch-associated scratching induced by 12-(S)-lipoxygenase products in ICR mice. Br J Pharmacol. 2008 Jul;154(5):1073-8. Epub 2008 Jun 9. To confirm the involvement of the BLT2 receptor in 12 (S)-HPETE-induced scratching, we studied the scratch response using the BLT2 receptor agonists compound A (4'-[[pentanoyl (phenyl) amino] methyl]-1,1'-biphenyl-2-carboxylic acid) and 12 (S)-HETE (12 (S)-hydroxyeicosa-5Z,8Z,10E,14Z-tetraenoic acid). |
2(0,0,0,2) | Details |
18991744 | Maria K, Dimitra HL, Maria G: Synthesis and anti-inflammatory activity of chalcones and related Mannich bases. Med Chem. 2008 Nov;4(6):586-96. Among the tested compounds 5 and 6 showed the highest lipoxygenase (LO) inhibitory activity. |
1(0,0,0,1) | Details |
19241532 | Min B, Nam KC, Cordray J, Ahn DU: Endogenous factors affecting oxidative stability of beef loin, pork loin, and chicken breast and thigh meats. J Food Sci. 2008 Aug;73(6):C439-46. TBARS values of raw BL, however, significantly increased during 7-d storage because of high heme iron content, high lipoxygenase-like activities, and low 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activities. |
1(0,0,0,1) | Details |
19150597 | Symeonidis T, Chamilos M, Hadjipavlou-Litina DJ, Kallitsakis M, Litinas KE: Synthesis of hydroxycoumarins and hydroxybenzo [f]- or [h] as lipid peroxidation inhibitors. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1139-42. Epub 2008 Dec 31. The compounds were tested in vitro for their ability: (i) to interact with 1,1-diphenyl-2-picryl-hydrazyl (DPPH) stable free radical, (ii) to inhibit lipid peroxidation, (iii) to scavenge the (iv) to inhibit the activity of soybean lipoxygenase and (v) to inhibit in vivo the carrageenin-induced rat paw edema. |
1(0,0,0,1) | Details |
19551737 | Kovala-Demertzi D, Hadjipavlou-Litina D, Primikiri A, Staninska M, Kotoglou C, Demertzis MA: Anti-inflammatory, antiproliferative, and radical-scavenging activities of tolfenamic acid and its metal complexes. Chem Biodivers. 2009 Jun;6(6):948-60. Their ability to inhibit soybean lipoxygenase, beta-glucuronidase, and trypsin-induced proteolysis was studied. |
1(0,0,0,1) | Details |
19853459 | Detsi A, Majdalani M, Kontogiorgis CA, Hadjipavlou-Litina D, Kefalas P: Natural and synthetic 2'-synthesis, characterization and evaluation of the antioxidant and soybean lipoxygenase inhibitory activity. Bioorg Med Chem. 2009 Dec 1;17(23):8073-85. Epub 2009 Oct 6. |
-chalcones and aurones: 2(0,0,0,2) | Details |
19504389 | Ali S, Yasmeen S, Afza N, Malik A, Iqbal L, Lateef M, Riaz N, Ashraf M: Mutiniside, new antioxidant phenolic glucoside from Abutilon muticum. J Asian Nat Prod Res. 2009;11(5):457-64. Compound 1 showed significant antioxidant activity while moderate inhibitory activity was observed against the enzyme lipoxygenase. |
1(0,0,0,1) | Details |