| Name | lipase |
|---|---|
| Synonyms | HGL; HPL; HGL; Human giant larvae homolog; LGL 2; LGL2; LLGL 2; LLGL2… |
| Name | biphenyl |
|---|---|
| CAS | 1,1′-biphenyl |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18721756 | Zvonok N, Pandarinathan L, Williams J, Johnston M, Karageorgos I, Janero DR, Krishnan SC, Makriyannis A: Covalent inhibitors of human monoacylglycerol lipase: ligand-assisted characterization of the catalytic site by mass spectrometry and mutational analysis. Chem Biol. 2008 Aug 25;15(8):854-62. The active site of recombinant hexa--tagged human monoacylglycerol lipase (hMGL) is characterized by mass spectrometry using the inhibitors 5-((biphenyl-4-yl) methyl)-N,N-dimethyl-2H-tetrazole-2-carboxamide (AM6701), and N-arachidonylmaleimide (NAM) as probes. |
82(1,1,1,2) | Details |
| 19727883 | Choo WS, Birch EJ, Stewart I: Radical scavenging activity of lipophilized products from transesterification of flaxseed oil with or Lipids. 2009 Sep;44(9):807-15. Lipase-catalyzed transesterification of flaxseed oil with (CA) or (FA) using an immobilized lipase from Candida antarctica (E.C. 3.1.1.3) was conducted to evaluate whether the lipophilized products provided enhanced antioxidant activity in the oil. |
3(0,0,0,3) | Details |
| 18948437 | Duncan M, Thomas AD, Cluny NL, Patel A, Patel KD, Lutz B, Piomelli D, Alexander SP, Sharkey KA: Distribution and function of monoacylglycerol lipase in the gastrointestinal tract. Am J Physiol Gastrointest Liver Physiol. 2008 Dec;295(6):G1255-65. Epub 2008 Oct 23. |
2(0,0,0,2) | Details |
| 18096498 | Imming P: Fatty pain cures. Chem Biol. 2007 Dec;14(12):1311-2. In this issue, Alvin King, Daniele Piomelli, and colleagues publish another interesting paper on inhibition of monoacylglycerol lipase (MGL). |
1(0,0,0,1) | Details |
| 19767452 | Straiker A, Hu SS, Long JZ, Arnold A, Wager-Miller J, Cravatt BF, Mackie K: Monoacylglycerol lipase limits the duration of endocannabinoid-mediated depolarization-induced suppression of excitation in autaptic hippocampal neurons. Mol Pharmacol. 2009 Dec;76(6):1220-7. Epub 2009 Sep 18. |
1(0,0,0,1) | Details |
| 18096504 | King AR, Duranti A, Tontini A, Rivara S, Rosengarth A, Clapper JR, Astarita G, Geaga JA, Luecke H, Mor M, Tarzia G, Piomelli D: URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices. Chem Biol. 2007 Dec;14(12):1357-65. The N-aryl URB602 (biphenyl-3-ylcarbamic acid cyclohexyl ester) is an inhibitor of monoacylglycerol lipase (MGL), a serine hydrolase involved in the biological deactivation of the endocannabinoid 2-arachidonoyl-sn- (2-AG). |
1(0,0,0,1) | Details |