| Name | 5 HT 2A |
|---|---|
| Synonyms | 5 HT 2; 5 HT 2A; 5 HT2; 5 HT2A; 5 hydroxytryptamine (serotonin) receptor 2A; 5 hydroxytryptamine 2A receptor; 5 hydroxytryptamine receptor 2A; HTR 2… |
| Name | biphenyl |
|---|---|
| CAS | 1,1′-biphenyl |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19479848 | Trachsel D, Nichols DE, Kidd S, Hadorn M, Baumberger F: 4-aryl-substituted 2,5-dimethoxyphenethylamines: synthesis and serotonin 5-HT (2A) receptor affinities. Chem Biodivers. 2009 May;6(5):692-704. Additionally, biphenyl compound 6 lacking the 5'-MeO substituent was prepared, starting from 2-methoxy-4-hydroxybenzaldehyde. |
3(0,0,0,3) | Details |
| 17880377 | Garcia M, Moran A, Martin ML, Ortizde Urbina AV, San Roman L: Diabetes-induced changes in modulation of vagally-induced bradycardia in rat heart. Clin Exp Pharmacol Physiol. 2007 Nov;34(11):1199-206. Enhancement of the electrical stimulation-induced bradycardia in diabetic rats caused by 5-CT (10 microg/kg) or 8-OH-DPAT (50 microg/kg) was abolished by the selective 5-HT (2/7) receptor antagonist mesulergine (1 mg/kg) and the selective 5-HT (1A) receptor antagonist WAY-100,635 (100 microg/kg), respectively. |
1(0,0,0,1) | Details |
| 19439499 | Molinaro G, Traficante A, Riozzi B, Di Menna L, Curto M, Pallottino S, Nicoletti F, Bruno V, Battaglia G: Activation of mGlu2/3 metabotropic glutamate receptors negatively regulates the stimulation of inositol phospholipid hydrolysis mediated by 5-hydroxytryptamine2A serotonin receptors in the frontal cortex of living mice. Mol Pharmacol. 2009 Aug;76(2):379-87. Epub 2009 May 13. The interaction between (2A) (5-HT (2A)) serotonin receptors and metabotropic (mGlu) 2/3 receptors underlies the antipsychotic activity of mGlu2/3 receptor agonists in experimental animals and humans. N-(4'-cyano-biphenyl-3-yl)-N-(3-pyridinylmethyl)-ethanesulfonamide hydrochloride (LY566332), a selective mGlu2 receptor enhancer, also reduced DOI-stimulated PI hydrolysis when combined with subthreshold doses of LY379268. |
5(0,0,0,5) | Details |