| Name | neurokinin 1 |
|---|---|
| Synonyms | Hs.2563; PPT; NK2; NKA; NKNA; Neurokinin 1; Neurokinin 2; Neurokinin A… |
| Name | biphenyl |
|---|---|
| CAS | 1,1′-biphenyl |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17945197 | Evans DL, Lynch KG, Benton T, Dube B, Gettes DR, Tustin NB, Lai JP, Metzger D, Douglas SD: Selective reuptake inhibitor and substance P antagonist enhancement of natural killer cell innate immunity in human immunodeficiency virus/acquired immunodeficiency syndrome. Biol Psychiatry. 2008 May 1;63(9):899-905. Epub 2007 Oct 22. |
3(0,0,0,3) | Details |
| 18187929 | Watanabe Y, Asai H, Ishii T, Kiuchi S, Okamoto M, Taniguchi H, Nagasaki M, Saito A: Pharmacological characterization of T-2328, 2--4'-methoxy-3'-[[[(2S,3S)-2-phenyl-3-piperidinyl] amino] methyl]-[1, 1'-biphenyl]-4-carbonitrile dihydrochloride, as a brain-penetrating antagonist of tachykinin NK1 receptor. J Pharmacol Sci. 2008 Jan;106(1):121-7. Epub 2008 Jan 11. The pharmacological properties of T-2328 were evaluated as an antagonist of the tachykinin neurokinin 1 (NK (1)) receptor. |
2(0,0,0,2) | Details |
| 18160487 | Ramnath RD, Sun J, Adhikari S, Zhi L, Bhatia M: Role of PKC-delta on substance P-induced chemokine synthesis in pancreatic acinar cells. Am J Physiol Cell Physiol. 2008 Mar;294(3):C683-92. Epub 2007 Dec 26. |
2(0,0,0,2) | Details |
| 19279355 | Yaraee R, Ghazanfari T: Substance P potentiates TGFbeta-1 production in lung epithelial cell lines. Iran J Allergy Asthma Immunol. 2009 Mar;8(1):19-24. |
2(0,0,0,2) | Details |
| 18326823 | Li PC, Chen WC, Chang LC, Lin SC: Substance P acts via the neurokinin receptor 1 to elicit bronchoconstriction, oxidative stress, and upregulated ICAM-1 expression after oil smoke exposure. Am J Physiol Lung Cell Mol Physiol. 2008 May;294(5):L912-20. Epub 2008 Mar 7. |
2(0,0,0,2) | Details |
| 19832997 | Lin YR, Chen HH, Lin YC, Ko CH, Chan MH: Antinociceptive actions of honokiol and magnolol on glutamatergic and inflammatory pain. J Biomed Sci. 2009 Oct 16;16:94. The antinociceptive effects of honokiol and magnolol, two major bioactive constituents of the bark of Magnolia officinalis, were investigated on animal paw licking responses and thermal hyperalgesia induced by glutamate receptor agonists including and metabotropic 5 receptor (mGluR5) activator (RS)-2-chloro-5-hydroxyphenylglycine (CHPG), as well as inflammatory mediators such as substance P and in mice. |
2(0,0,0,2) | Details |
| 18809416 | Tang HB, Li YS, Miyano K, Nakata Y: Phosphorylation of TRPV1 by neurokinin-1 receptor agonist exaggerates the -mediated substance P release from cultured rat dorsal root ganglion neurons. Neuropharmacology. 2008 Dec;55(8):1405-11. Epub 2008 Sep 17. |
2(0,0,0,2) | Details |
| 18930727 | Haddjeri N, Blier P: Neurokinin-1 receptor antagonists modulate brain and interactions. Eur J Pharmacol. 2008 Dec 14;600(1-3):64-70. Epub 2008 Oct 9. Substance P (neurokinin-1; NK1) receptor antagonists represent a putative new class of antidepressant/anxiolytic drugs. |
1(0,0,0,1) | Details |