| Name | PC 3 |
|---|---|
| Synonyms | PC 3; secreted microprotein PC 3; secreted microprotein PC 3s |
| Name | biphenyl |
|---|---|
| CAS | 1,1′-biphenyl |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18281560 | Hahm ER, Arlotti JA, Marynowski SW, Singh SV: Honokiol, a constituent of oriental medicinal herb magnolia officinalis, inhibits growth of PC-3 xenografts in vivo in association with apoptosis induction. Clin Cancer Res. 2008 Feb 15;14(4):1248-57. |
5(0,0,0,5) | Details |
| 17938262 | Hahm ER, Singh SV: Honokiol causes G0-G1 phase cell cycle arrest in human prostate cancer cells in association with suppression of retinoblastoma protein level/phosphorylation and inhibition of E2F1 transcriptional activity. Mol Cancer Ther. 2007 Oct;6(10):2686-95. The honokiol treatment decreased the viability of PC-3 and LNCaP human prostate cancer cells in a concentration- and time-dependent manner, which correlated with G0-G1 phase cell cycle arrest. |
3(0,0,0,3) | Details |
| 19229860 | Lee DH, Szczepanski MJ, Lee YJ: Magnolol induces apoptosis via inhibiting the EGFR/PI3K/Akt signaling pathway in human prostate cancer cells. J Cell Biochem. 2009 Apr 15;106(6):1113-22. Treatment of PC-3 cells with an apoptosis-inducing concentration of magnolol (60 microM) resulted in a rapid decrease in the level of phosphorylated Akt leading to inhibition of its kinase activity. |
1(0,0,0,1) | Details |
| 18056461 | Garrison JB, Shaw YJ, Chen CS, Kyprianou N: Novel quinazoline-based compounds impair prostate tumorigenesis by targeting tumor vascularity. Cancer Res. 2007 Dec 1;67(23):11344-52. In vivo tumorigenicty studies using two androgen-independent human prostate cancer xenografts, PC-3 and DU-145, showed that DZ-50 treatment leads to significant suppression of tumorigenic growth. |
1(0,0,0,1) | Details |
| 20183253 | Wang YN, Tian L, Hua HM, Lu X, Sun S, Wu HH, Pei YH: Two new compounds from the broth of the marine fungus Penicillium griseofulvum Y19-07. J Asian Nat Prod Res. 2009 Nov;11(11):912-7. Also, in the cytotoxicity assay of the two new compounds against HL-60 and PC-3 prostate cancer cell lines, compound 2 showed potential activity with an IC (50) value of 64.5 microM against human HL-60 cancer cells. |
1(0,0,0,1) | Details |
| 18241858 | Lee SY, Yuk DY, Song HS, Yoon do Y, Jung JK, Moon DC, Lee BS, Hong JT: Growth inhibitory effects of obovatol through induction of apoptotic cell death in prostate and colon cancer by blocking of NF-kappaB. Eur J Pharmacol. 2008 Mar 17;582(1-3):17-25. Epub 2008 Jan 5. We investigated here whether obovatol could inhibit NF-kappaB activity, and thereby inhibit cancer cell growth in prostate (LNCaP and PC-3) and colon cancer (SW620 and HCT116) cells. |
1(0,0,0,1) | Details |
| 19834284 | Lee SY, Cho JS, Yuk DY, Moon DC, Jung JK, Yoo HS, Lee YM, Han SB, Oh KW, Hong JT: Obovatol enhances docetaxel-induced prostate and colon cancer cell death through inactivation of nuclear transcription factor-kappaB. J Pharmacol Sci. 2009 Oct;111(2):124-36. We investigated here whether obovatol could sensitize cancer cells against docetaxel through inhibition of NF-kappaB activity in prostate cancer (LNCaP and PC-3) and colon cancer (SW620 and HCT116) cells. |
1(0,0,0,1) | Details |