Protein Information

Name myeloperoxidase
Synonyms 38 kDa MYELOPEROXIDASE; MPO; Myeloperoxidase; Myeloperoxidase precursor; Peroxidase (Myeloperoxidase); Myeloperoxidases; Myeloperoxidase precursors; Peroxidase (Myeloperoxidase)s

Compound Information

Name biphenyl
CAS 1,1′-biphenyl

Reference List

PubMed Abstract RScore(About this table)
19328559 Franck T, Kohnen S, de la Rebiere G, Deby-Dupont G, Deby C, Niesten A, Serteyn D: Activation of equine neutrophils by phorbol myristate acetate or N-formyl-methionyl-leucyl-phenylalanine induces a different response in reactive oxygen species production and release of active myeloperoxidase. Vet Immunol Immunopathol. 2009 Aug 15;130(3-4):243-50. Epub 2009 Mar 4.

2(0,0,0,2) Details
19161677 Vieira TO, Said A, Aboutabl E, Azzam M, Creczynski-Pasa TB: Antioxidant activity of methanolic extract of Bombax ceiba. Redox Rep. 2009;14(1):41-6.


The antioxidant activity of a methanolic extract of Bombax ceiba was evaluated using several antioxidant assays, in terms of its: (i) ability to scavenge DPPH (1,1-diphenyl-2-picryl-hydrazyl) and hydroxyl free radicals; (ii) action against lipid peroxidation (in rat liver microsomes and soy bean phosphatidylcholine liposomes), induced by ascorbyl radicals and peroxynitrite; and (iii) effect on myeloperoxidase activity.
2(0,0,0,2) Details
18451567 Fernandes DC, Regasini LO, Vellosa JC, Pauletti PM, Castro-Gamboa I, Bolzani VS, Oliveira OM, Silva DH: Myeloperoxidase inhibitory and radical scavenging activities of flavones from Pterogyne nitens. Chem Pharm Bull. 2008 May;56(5):723-6.

2(0,0,0,2) Details
18601970 Vardi N, Parlakpinar H, Ozturk F, Ates B, Gul M, Cetin A, Erdogan A, Otlu A: Potent protective effect of apricot and beta-carotene on methotrexate-induced intestinal oxidative damage in rats. Food Chem Toxicol. 2008 Sep;46(9):3015-22. Epub 2008 Jun 14.


Parallel to histological results, malondialdehyde (MDA) content and myeloperoxidase (MPO) activity were found to be increased, whereas superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GP-x) activities and glutathione (GSH) content were decreased in the MTX group.
1(0,0,0,1) Details
19577912 Chen HY, Hung YC, Lee EJ, Chen TY, Chuang IC, Wu TS: The protective efficacy of magnolol in hind limb ischemia-reperfusion injury. Phytomedicine. 2009 Oct;16(10):976-81. Epub 2009 Jul 4.


At 24 h post-insult, the levels of nitrite/nitrate (NOX), malondialdehyde (MDA) and myeloperoxidase (MPO), as well as the degree of muscle damage, were assessed.
1(0,0,0,1) Details
19445998 Kong CS, Kim JA, Qian ZJ, Kim YA, Lee JI, Kim SK, Nam TJ, Seo Y: Protective effect of isorhamnetin 3-O-beta-D-glucopyranoside from Salicornia herbacea against oxidation-induced cell damage. Food Chem Toxicol. 2009 Aug;47(8):1914-20. Epub 2009 May 13.


In addition, it significantly inhibited oxidative damage of purified genomic DNA and suppressed activity of myeloperoxidase (MPO), a generator of potent oxidant (hypochlorous acid), in tumor necrosis factor-alpha (TNF-alpha) stimulated human myeloid cells.
1(0,0,0,1) Details
18784584 Anaya-Prado R, Perez-Gomez N, Toledo-Pereyra LH, Walsh J, Jordan J, Ward PA: Small molecule selectin inhibitor in global cerebral ischemia and controlled hemorrhagic shock. J Trauma. 2008 Sep;65(3):678-84.


The following indices were evaluated: brain tissue myeloperoxidase, average numbers of ischemic neurons, and 7-day survival.
1(0,0,0,1) Details