| PubMed |
Abstract |
RScore(About this table) |
| 18276145 |
Colabufo NA, Berardi F, Cantore M, Perrone MG, Contino M, Inglese C, Niso M, Perrone R, Azzariti A, Simone GM, Paradiso A: 4-Biphenyl and 2-naphthyl substituted 6,7-dimethoxytetrahydroisoquinoline derivatives as potent P-gp modulators. Bioorg Med Chem. 2008 Apr 1;16(7):3732-43. Epub 2008 Feb 2.
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84(1,1,1,4) |
Details |
| 18621528 |
Fish PV, Barta NS, Gray DL, Ryckmans T, Stobie A, Wakenhut F, Whitlock GA: Derivatives of (3S)-N-(biphenyl-2-ylmethyl) pyrrolidin-3-amine as selective noradrenaline reuptake inhibitors: Reducing P-gp mediated efflux by modulation of H-bond acceptor capacity. Bioorg Med Chem Lett. 2008 Aug 1;18(15):4355-9. Epub 2008 Jun 25.
|
82(1,1,1,2) |
Details |
| 19264347 |
Bonfanti P, Colombo A, Villa S, Comelli F, Costa B, Santagostino A: The effects of accumulation of an environmentally relevant polychlorinated biphenyl mixture on cytochrome P450 and P-glycoprotein expressions in fetuses and pregnant rats. Chemosphere. 2009 May;75(5):572-9. Epub 2009 Mar 4.
|
7(0,0,1,2) |
Details |
| 19914261 |
Kamiyama E, Nakai D, Mikkaichi T, Okudaira N, Okazaki O: Interaction of angiotensin II type 1 receptor blockers with P-gp substrates in Caco-2 cells and hMDR1-expressing membranes. Life Sci. 2010 Jan 2;86(1-2):52-8. Epub 2009 Nov 13.
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5(0,0,0,5) |
Details |
| 18801310 |
Tan W, Chen H, Zhao J, Hu J, Li Y: A study of intestinal absorption of bicyclol in rats: active efflux transport and metabolism as causes of its poor bioavailability. J Pharm Pharm Sci. 2008;11(3):97-105.
PURPOSE: To determine the possible mechanism of poor bioavailability of bicyclol, and clarify the respective contribution of P- glycoprotein (P-gp) and Cytochrome 3A (CYP3A). |
4(0,0,0,4) |
Details |