| Name | beta glucuronidase |
|---|---|
| Synonyms | Beta glucuronidase; Beta G1; Beta glucuronidase precursor; GUSB; MPS 7; MPS7; Beta G1s; Beta glucuronidase precursors |
| Name | pentachlorophenol |
|---|---|
| CAS | 2,3,4,5,6-pentachlorophenol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 327981 | Ahlborg UG, Manzoor E, Thunberg T: Inhibition of beta-glucuronidase by chlorinated hydroquinones and benzoquinones. Arch Toxicol. 1977 Jun 18;37(2):81-7. An earlier study of the metabolism of pentachlorophenol has shown that a metabolite, tetrachloro- possessed pronounced inhibitory action on the activity of beta-glucuronidase from bacterial origin. |
85(1,1,1,5) | Details |
| 15171687 | van der Heide SM, Joosten BJ, Everts ME, Klaren PH: Activities of UDP-glucuronyltransferase, beta-glucuronidase and deiodinase types I and II in hyper- and hypothyroid rats. J Endocrinol. 2004 Jun;181(3):393-400. |
5(0,0,0,5) | Details |
| 1879408 | George SE, Chadwick RW, Creason JP, Kohan MJ, Dekker JP: Effect of pentachlorophenol on the activation of 2,6-dinitrotoluene to genotoxic urinary metabolites in CD-1 mice: a comparison of GI enzyme activities and urine mutagenicity. Environ Mol Mutagen. 1991;18(2):92-101. At weeks 2 and 4, mice were sacrificed and intestinal enzyme activities (nitroreductase, azo reductase, beta-glucuronidase, dechlorinase, and dehydrochlorinase) were quantitated. |
2(0,0,0,2) | Details |
| 580375 | Ahlborg UG, Larsson K, Thunberg T: Metabolism of pentachlorophenol in vivo and in vitro. Arch Toxicol. 1978 Feb 21;40(1):45-53. Bovine liver beta-glucuronidase has been utlizied to split the conjugates present. |
1(0,0,0,1) | Details |
| 15866492 | Kawaguchi M, Sakui N, Okanouchi N, Ito R, Saito K, Izumi S, Makino T, Nakazawa H: Stir bar sorptive extraction with in situ derivatization and thermal desorption-gas chromatography--mass spectrometry for measurement of phenolic xenoestrogens in human urine samples. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Jun 5;820(1):49-57. Epub 2005 Apr 19. A high-sensitivity analytical method that uses stir bar sorptive extraction (SBSE) with in situ derivatization and thermal desorption (TD)-gas chromatography-mass spectrometry (GC-MS) for the simultaneous measurement of trace amounts of phenolic xenoestrogens (PXs), such as (DCP), 4-tert-butylphenol (BP), 4-tert-octylphenol (OP), 4-nonylphenol technical isomers (NP), pentachlorophenol (PCP) and bisphenol A (BPA), in human urine samples was developed. The urine sample (1 ml) was de-conjugated by adding beta-glucuronidase and sulfatase. |
1(0,0,0,1) | Details |
| 3553529 | Mori M, Sayama M, Futagami M, Naito M, Miyahara T, Kozuka H: Mutagenicity of some hydroxylaminotoluene derivatives towards Salmonella typhimurium in esterification systems. J Pharmacobiodyn. 1986 Dec;9(12):1036-9. The indirect mutagenic activity was markedly decreased by omission of microsomal fraction (MCF) or UDPGA from the UDPGA system and by addition of beta-glucuronidase to the system. Similarly, the mutagenic activity was markedly decreased either when 105000 X g supernatant fluid (S105), (ATP) or Na2SO4 was omitted from the system or when pentachlorophenol (PCP) or aryl sulphatase was added to the system. |
1(0,0,0,1) | Details |
| 18676208 | Ito R, Kawaguchi M, Honda H, Koganei Y, Okanouchi N, Sakui N, Saito K, Nakazawa H: Hollow-fiber-supported liquid phase microextraction with in situ derivatization and gas chromatography-mass spectrometry for determination of chlorophenols in human urine samples. J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Sep 1;872(1-2):63-7. Epub 2008 Jul 15. A simple and highly sensitive method that involves hollow-fiber-supported liquid phase microextraction (HF-LPME) with in situ derivatization and gas chromatography-mass spectrometry (GC-MS) was developed for the determination of chlorophenols (CPs) such as (DCP), 2,4,6-trichlorophenol (TrCP), 2,3,4,6-tetrachlorophenol (TeCP) and pentachlorophenol (PCP) in human urine samples. Human urine samples were enzymatically de-conjugated with beta-glucuronidase and sulfatase. |
1(0,0,0,1) | Details |