Name | hemoglobin (protein family or complex) |
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Synonyms | Hemoglobin; Hemoglobins |
Name | pentachlorophenol |
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CAS | 2,3,4,5,6-pentachlorophenol |
PubMed | Abstract | RScore(About this table) | |
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8728511 | Waidyanatha S, Lin PH, Rappaport SM: Characterization of chlorinated adducts of hemoglobin and albumin following administration of pentachlorophenol to rats. Chem Res Toxicol. 1996 Apr-May;9(3):647-53. |
32(0,1,1,2) | Details |
8870951 | Wilson PM, La DK, Froines JR: Hemoglobin and DNA adduct formation in Fischer-344 rats exposed to 2,4- and 2,6-toluene diamine. Arch Toxicol. 1996;70(10):591-8. The effects of metabolic inhibitors on adduct formation were examined using piperonyl butoxide and pentachlorophenol to inhibit p450 isozymes and sulfotransferase, respectively. |
7(0,0,0,7) | Details |
8075381 | Waidyanatha S, McDonald TA, Lin PH, Rappaport SM: Measurement of hemoglobin and albumin adducts of tetrachlorobenzoquinone. Chem Res Toxicol. 1994 May-Jun;7(3):463-8. Tetrachloro- (Cl4BQ), a metabolite of pentachlorophenol (PCP), is believed to play a role in the genotoxicity of PCP. |
2(0,0,0,2) | Details |
12415425 | Tsai CH, Lin PH, Waidyanatha S, Rappaport SM: Fractionation of protein adducts in rats and mice dosed with [14C] pentachlorophenol. Arch Toxicol. 2002 Nov;76(11):628-33. Epub 2002 Sep 20. Using a sequential scheme of scintillation counting along with selective cleavage of cysteinyl adducts by we quantified total radiobinding, total covalent binding, non-cysteinyl protein binding, and specific protein adducts in liver nuclei (Np), liver cytosol (Cp), hemoglobin (Hb), and serum albumin (Alb). |
1(0,0,0,1) | Details |
3265913 | Oikari A, Linstrom-Seppa P, Kukkonen J: Subchronic metabolic effects and toxicity of a simulated pulp mill effluent on juvenile lake trout, Salmo trutta m. lacustris. Ecotoxicol Environ Saf. 1988 Dec;16(3):202-18. In addition, a small (9%) but significant decrease in blood hemoglobin concentration was observed at the higher exposure concentration. The greatest total gradient between bile and water CP was 5.2 X 10 (4) for pentachlorophenol. |
1(0,0,0,1) | Details |