| Name | aryl sulfotransferase |
|---|---|
| Synonyms | Aryl sulfotransferase; Aryl sulfotransferase 1A3; Catecholamine sulfating phenol sulfotransferase; Dopamine specific sulfotransferase; HAST; HAST 3; HAST3; M PST… |
| Name | pentachlorophenol |
|---|---|
| CAS | 2,3,4,5,6-pentachlorophenol |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 7521230 | Sodum RS, Sohn OS, Nie G, Fiala ES: Activation of the liver carcinogen 2-nitropropane by aryl sulfotransferase. Chem Res Toxicol. 1994 May-Jun;7(3):344-51. Pretreatment of rats with the aryl sulfotransferase inhibitors pentachlorophenol or 2,6-dichloro- significantly decreased the levels of liver nucleic acid modifications produced by 2-NP treatment. |
34(0,1,1,4) | Details |
| 6349633 | Nagao M, Fujita Y, Wakabayashi K, Sugimura T: Ultimate forms of mutagenic and carcinogenic heterocyclic amines produced by pyrolysis. Biochem Biophys Res Commun. 1983 Jul 29;114(2):626-31. The mutagenicities of some of these heterocyclic amines to TA98 were inhibited by pentachlorophenol, an aryl sulfotransferase inhibitor. |
31(0,1,1,1) | Details |
| 2401045 | Mangold BL, Erickson J, Lohr C, McCann DJ, Mangold JB: Self-catalyzed irreversible inactivation of rat hepatic aryl sulfotransferase IV by N--2-acetylaminofluorene. Carcinogenesis. 1990 Sep;11(9):1563-7. The inactivation was dependent and blocked by the sulfotransferase inhibitor, pentachlorophenol. |
5(0,0,0,5) | Details |
| 1733562 | Ringer DP, Norton TR, Self RR: Reaction product inactivation of aryl sulfotransferase IV following electrophilic substitution by the sulfuric acid ester of N--2-acetylaminofluorene. Carcinogenesis. 1992 Jan;13(1):107-12. The labeling could be blocked if the sulfotransferase inhibitor pentachlorophenol was present. |
2(0,0,0,2) | Details |
| 10799342 | Duanmu Z, Dunbar J, Falany CN, Runge-Morris M: Induction of rat hepatic aryl sulfotransferase (SULT1A1) gene expression by triamcinolone acetonide: impact on minoxidil-mediated hypotension. Toxicol Appl Pharmacol. 2000 May 1;164(3):312-20. Pentachlorophenol (PCP, 40 micromol/kg i.p.), an inhibitor of SULT1 enzyme activity, effectively ablated the hypotensive effects of minoxidil. |
2(0,0,0,2) | Details |
| 3478156 | Ringer DP, Norton TR: Further characterization of the ability of hepatocarcinogens to lower rat liver aryl sulfotransferase activity. Carcinogenesis. 1987 Nov;8(11):1749-52. We also determined whether the co-administration of the AST enzyme inhibitor, pentachlorophenol, with hepatocarcinogens will abrogate the lowering of AST activity caused by hepatocarcinogens which do not utilize AST for bio-activation versus hepatocarcinogens which can utilize AST. |
2(0,0,0,2) | Details |
| 12167648 | Tulik GR, Chodavarapu S, Edgar R, Giannunzio L, Langland A, Schultz B, Beckmann JD: Inhibition of bovine phenol sulfotransferase (bSULT1A1) by thioesters. J Biol Chem. 2002 Oct 18;277(42):39296-303. Epub 2002 Aug 6. Second, prevented the quenching of bSULT1A1 fluorescence observed with pentachlorophenol. Here we report that long chain acyl-CoAs are more potent inhibitors of bSULT1A1 and also of human sulfotransferase (SULT1A3) when compared with unesterified and short chain-length acyl-CoAs. |
1(0,0,0,1) | Details |