| Name | caspase (protein family or complex) |
|---|---|
| Synonyms | caspase; caspases |
| Name | diphenylamine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 11108134 | von Knethen A, Brune B: Attenuation of macrophage apoptosis by the cAMP-signaling system. Mol Cell Biochem. 2000 Sep;212(1-2):35-43. Selected apoptotic parameters comprised DNA fragmentation (diphenylamine assay), annexin V staining of caspase activity (quantitated by the cleavage of a fluorogenic caspase-3-like substrate Ac-DEVD-AMC), and mitochondrial membrane depolarisation (delta psi). |
31(0,1,1,1) | Details |
| 10602776 | von Knethen A, Brockhaus F, Kleiter I, Brune B: NO-Evoked macrophage apoptosis is attenuated by cAMP-induced gene expression. Mol Med. 1999 Oct;5(10):672-84. Parameters comprised DNA fragmentation (diphenylamine assay), annexin V staining of caspase activity (quantitated by the cleavage of a fluorogenic caspase-3-like substrate Ac-DEVD-AMC), and mitochondrial membrane depolarization (DeltaPsi), analyzed using DiOC (6)(3). |
31(0,1,1,1) | Details |
| 18583568 | Lunghi P, Giuliani N, Mazzera L, Lombardi G, Ricca M, Corradi A, Cantoni AM, Salvatore L, Riccioni R, Costanzo A, Testa U, Levrero M, Rizzoli V, Bonati A: Targeting MEK/MAPK signal transduction module potentiates ATO-induced apoptosis in multiple myeloma cells through multiple signaling pathways. Blood. 2008 Sep 15;112(6):2450-62. Epub 2008 Jun 26. We demonstrate that blockade of the MEK/ERK signaling module, using the small-molecule inhibitors PD184352 or PD325901 (PD), strikingly enhances arsenic trioxide (ATO)-induced cytotoxicity in human myeloma cell lines (HMCLs) and in tumor cells from patients with multiple myeloma (MM) through a caspase-dependent mechanism. |
2(0,0,0,2) | Details |
| 12628314 | Melo PS, Justo GZ, de Azevedo MB, Duran N, Haun M: Violacein and its beta-cyclodextrin complexes induce apoptosis and differentiation in HL60 cells. Toxicology. 2003 Apr 22;186(3):217-25. Moreover, by using the Feulgen reaction, all the compounds were found to trigger apoptosis in HL60 cells, inducing around 35% of DNA fragmentation, as analyzed through the diphenylamine assay. In addition, caspases seem to play an important role in the activation of the executioner phase of apoptosis induced by violacein and its derivatives. |
1(0,0,0,1) | Details |
| 15538571 | Zhang XM, Chen J, Xia YG, Xu Q: Apoptosis of murine melanoma B16-BL6 cells induced by targeting mitochondria, inhibiting expression of PKC-alpha and translocating PKC-delta. Cancer Chemother Pharmacol. 2005 Mar;55(3):251-62. Epub 2004 Nov 5. DNA fragmentation was analyzed by electrophoresis and quantified by the diphenylamine method. Caspase activity was determined spectrophotometrically. |
1(0,0,0,1) | Details |