Protein Information

Name alpha fetoprotein
Synonyms AFP; Alpha fetoprotein; Alpha 1 fetoprotein; Alpha fetoglobulin; Alpha fetoprotein precursor; FETA; HPAFP; Alpha fetoproteins…

Compound Information

Name allyl alcohol
CAS 2-propen-1-ol

Reference List

PubMed Abstract RScore(About this table)
9537443 Petersen BE, Zajac VF, Michalopoulos GK: Hepatic oval cell activation in response to injury following chemically induced periportal or pericentral damage in rats. Hepatology. 1998 Apr;27(4):1030-8.

Our objective in this study was to examine the oval cell response and associated alpha-fetoprotein (AFP) gene expression by combining 2-AAF with selective damage of centrilobular regions (carbon tetrachloride [CCl4]) or periportal regions (allyl alcohol [AA]).
6(0,0,1,1) Details
70250 Lazareva MN: [Characteristics of hepatocytes containing alpha-fetoprotein in regenerating mouse liver]. Biull Eksp Biol Med. 1977 Jul;84(7):97-101.

Analgous localization of the alpha-FP-containing cells was found in the liver of mice poisoned with two other hepatotoxins--paracetamol and allyl alcohol.
2(0,0,0,2) Details
7539398 Yavorkovsky L, Lai E, Ilic Z, Sell S: Participation of small intraportal stem cells in the restitutive response of the liver to periportal necrosis induced by allyl alcohol. Hepatology. 1995 Jun;21(6):1702-12.

Adult female Sprague-Dawley rats were injected intraperitoneally (IP) with 0.62 mmol/kg AA, killed at 6, 9, 12, 33, 57, 81, and 153 hours after injection, and the livers were examined for injury and for restitutive proliferation by histology, autoradiography, and immunohistochemistry to detect alpha-fetoprotein (AFP), glutathione-s-transferase-p (GST-p), desmin, leukocyte common antigen, albumin, and monoclonal antibodies to liver cells: OV-6, H-4, and T-6.
1(0,0,0,1) Details
12832698 Zhang M, Sell S, Leffert HL: Hepatic progenitor cell lines from allyl alcohol-treated adult rats are derived from gamma-irradiated mouse STO cells. Stem Cells. 2003;21(4):449-58.

0(0,0,0,0) Details