Protein Information

Name hemoglobin (protein family or complex)
Synonyms Hemoglobin; Hemoglobins

Compound Information

Name allyl alcohol
CAS 2-propen-1-ol

Reference List

PubMed Abstract RScore(About this table)
2222504 Ferrali M, Ciccoli L, Signorini C, Comporti M: Iron release and erythrocyte damage in allyl alcohol intoxication in mice. Biochem Pharmacol. 1990 Oct 1;40(7):1485-90.

Studies carried out with reconstituted systems of erythrocyte lysates, containing ghosts and different fractions of erythrocyte cytosol and incubated in the presence of acrolein (the major metabolite of allyl alcohol), strongly suggest that iron is released from hemoglobin.
31(0,1,1,1) Details
3319769 Hall JG, Wills C: Conditional overdominance at an alcohol dehydrogenase locus in yeast. Genetics. 1987 Nov;117(3):421-7.

Documented examples of heterosis attributable to overdominance at specific protein-encoding gene loci have rarely been reported, the association of sickle cell hemoglobin with malarial resistance being the best documented example of this phenomenon.
Here we report an example of overdominance that is temperature- and allyl alcohol-dependent and due to heterozygosity at the ADH1 locus, involving two ADHI functional mutants.
2(0,0,0,2) Details