Protein Information

Name thymidine kinase
Synonyms Mt TK; TK2; Thymidine kinase; Thymidine kinase 2 isoform B; Thymidine kinases; Thymidine kinase 2 isoform Bs

Compound Information

Name furfural
CAS 2-furancarboxaldehyde

Reference List

PubMed Abstract RScore(About this table)
8075362 Surh YJ, Tannenbaum SR: Activation of the Maillard reaction product 5-(hydroxymethyl) furfural to strong mutagens via allylic sulfonation and chlorination. Chem Res Toxicol. 1994 May-Jun;7(3):313-8.

In support of this concept, the chemically synthesized sulfuric acid ester,5-[(sulfooxy)-methyl] furfural (SMF), exhibited direct mutagenicity at both thymidine kinase and hypoxanthine-guanine phosphoribosyltransferase loci in human lymphoblasts.
31(0,1,1,1) Details