| Name | caspase 3 |
|---|---|
| Synonyms | Apopain; CASP 3; CASP3; CPP 32; CPP32; CPP32B; Caspase 3; Caspase 3 precursor… |
| Name | OCH |
|---|---|
| CAS | 2,3,4,4,5,5,6,6-octachloro-2-cyclohexen-1-one |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10738248 | Gajate C, Santos-Beneit AM, Macho A, Lazaro M, Hernandez-De Rojas A, Modolell M, Munoz E, Mollinedo F: Involvement of mitochondria and caspase-3 in ET-18-OCH (3)-induced apoptosis of human leukemic cells. Int J Cancer. 2000 Apr 15;86(2):208-18. |
3(0,0,0,3) | Details |
| 12605983 | Dai S, Huang ML, Hsu CY, Chao KS: Inhibition of hypoxia inducible factor 1alpha causes -independent cytotoxicity and induces p53 independent apoptosis in glioblastoma cells. Int J Radiat Oncol Biol Phys. 2003 Mar 15;55(4):1027-36. Apoptotic cell death was detected with a colorimetric caspase-3 assay, as well as using terminal transferase-catalyzed in situ end labeling (TUNEL) staining. |
2(0,0,0,2) | Details |
| 10834929 | Bae SS, Perry DK, Oh YS, Choi JH, Galadari SH, Ghayur T, Ryu SH, Hannun YA, Suh PG: Proteolytic cleavage of phospholipase C-gamma1 during apoptosis in Molt-4 cells. FASEB J. 2000 Jun;14(9):1083-92. Purified caspase-3 and caspase-7, group II caspases, cleaved PLC-gamma1 in vitro and generated a cleavage product of the same size as that observed in vivo, suggesting that PLC-gamma1 is cleaved by group II caspases in vivo. |
2(0,0,0,2) | Details |
| 19447373 | Yslas EI, Prucca C, Romanini S, Durantini EN, Bertuzzi M, Rivarola V: Biodistribution and phototherapeutic properties of (II) 2,9,16,23-tetrakis (methoxy) phthalocyanine in vivo. Photodiagnosis Photodyn Ther. 2009 Mar;6(1):62-70. Epub 2009 Apr 14. In the tumor sections for biochemical studies, apoptosis was visualized by activation of caspase-3. |
1(0,0,0,1) | Details |
| 11919192 | Sitailo LA, Tibudan SS, Denning MF: Activation of caspase-9 is required for UV-induced apoptosis of human keratinocytes. J Biol Chem. 2002 May 31;277(22):19346-52. Epub 2002 Mar 27. UV radiation triggered activation of caspase-3, caspase-9, and caspase-8 with similar kinetics, although the rank order of activation was caspase-3 > caspase-9 > caspase-8. |
1(0,0,0,1) | Details |
| 12660222 | Maccarrone M, Battista N, Meloni M, Bari M, Galleri G, Pippia P, Cogoli A, Finazzi-Agro A: Creating conditions similar to those that occur during exposure of cells to microgravity induces apoptosis in human lymphocytes by 5-lipoxygenase-mediated mitochondrial uncoupling and cytochrome c release. J Leukoc Biol. 2003 Apr;73(4):472-81. The caspase-3 and caspase-9 inhibitors Z-Asp (OCH (3))- (OCH (3))-Val-Asp (OCH (3))-fluoromethylketone (FMK) and Z-- (OCH (3))-His-Asp (OCH (3))-FMK reduced apoptotic bodies to 25-30% of the control cells. |
1(0,0,0,1) | Details |
| 17955493 | Chow JM, Huang GC, Shen SC, Wu CY, Lin CW, Chen YC: Differential apoptotic effect of wogonin and nor-wogonin via stimulation of ROS production in human leukemia cells. J Cell Biochem. 2008 Apr 1;103(5):1394-404. Apoptotic characteristics including DNA ladders, apoptotic bodies, and hypodiploid cells accompanied by the induction of caspase 3 protein processing appeared in Wog- and N-Wog-treated HL-60 cells. |
1(0,0,0,1) | Details |