Protein Information

Name PI PLC
Synonyms Inositoltrisphosphohydrolase; PI PLC; Monophosphatidylinositol phosphodiesterase; Phosphoinositidase C; Phosphoinositide phospholipase C; Triphosphoinositide phosphodiesterase; PLC beta 4; PLCB 4…

Compound Information

Name OCH
CAS 2,3,4,4,5,5,6,6-octachloro-2-cyclohexen-1-one

Reference List

PubMed Abstract RScore(About this table)
15194239 Piacentini MP, Piatti E, Fraternale D, Ricci D, Albertini MC, Accorsi A: Phospholipase C-dependent phosphoinositide breakdown induced by ELF-EMF in Peganum harmala calli. Biochimie. 2004 Apr-May;86(4-5):343-9.

The manipulation of the lipid-based signalling pathway by phosphoinositide-phospholipase C (PI-PLC) inhibitors (i.e., neomycin, U-73122 and ET-18-OCH (3)) seems to support the hypothesis that, as in animals, also in plants, the cell membrane is the primary impact site of ELF electromagnetic stimulus and that this interaction could probably involve the activation of PI signal transduction pathway including a heterotrimeric G protein.
31(0,1,1,1) Details