Name | protein kinase C (protein family or complex) |
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Synonyms | Protein kinase C; PKC |
Name | OCH |
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CAS | 2,3,4,4,5,5,6,6-octachloro-2-cyclohexen-1-one |
PubMed | Abstract | RScore(About this table) | |
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16243962 | Braverman AS, Doumanian LR, Ruggieri MR Sr: M2 and M3 muscarinic receptor activation of urinary bladder contractile signal transduction. J Pharmacol Exp Ther. 2006 Feb;316(2):875-80. Epub 2005 Oct 21. Inhibition of PKC with chelerythrine increases darifenacin affinity, whereas inhibition of rho kinase, PKA, PKG, and protein kinase C (PKC) with 1-(5-isoquinolinesulfonyl)-2-methylpiperazine.2HCl (H7) reduces the carbachol potency while increasing darifenacin affinity. |
1(0,0,0,1) | Details |
17142672 | Lacchini AH, Davies AJ, Mackintosh D, Walker AJ: Beta-1, 3-glucan modulates PKC signalling in Lymnaea stagnalis defence cells: a role for PKC in H2O2 production and downstream ERK activation. J Exp Biol. 2006 Dec;209(Pt 24):4829-40. Haemocytes from the gastropod snail Lymnaea stagnalis (Linnaeus) were used as a model to characterize protein kinase C (PKC) signalling events in molluscan defence cells. |
1(0,0,0,1) | Details |
18067888 | McNally AK, Macewan SR, Anderson JM: Foreign body-type multinucleated giant cell formation requires protein kinase C beta, delta, and zeta. Exp Mol Pathol. 2008 Feb;84(1):37-45. Epub 2007 Nov 9. |
2(0,0,0,2) | Details |
20045694 | Almeida-Amaral EE, Cardoso VC, Francioli FG, Meyer-Fernandes JR: Leishmania amazonensis: heme stimulates (Na (+)+K (+)) ATPase activity via phosphatidylinositol-specific phospholipase C/protein kinase C-like (PI-PLC/PKC) signaling pathways. Exp Parasitol. 2010 Apr;124(4):436-41. Epub 2010 Jan 4. |
2(0,0,0,2) | Details |
18072286 | Weng JY, Hsu TT, Sun SH: Functional characterization of P2Y1 versus P2X receptors in RBA-2 astrocytes: elucidate the roles of ATP release and protein kinase C. J Cell Biochem. 2008 May 15;104(2):554-67. |
2(0,0,0,2) | Details |
16243961 | Braverman AS, Tibb AS, Ruggieri MR Sr: M2 and M3 muscarinic receptor activation of urinary bladder contractile signal transduction. J Pharmacol Exp Ther. 2006 Feb;316(2):869-74. Epub 2005 Oct 21. Inhibition of protein kinase C (PKC) with chelerythrine increases darifenacin affinity, whereas inhibition of rho kinase, PKA, PKG, and PKC with 1-(5-isoquinolinesulfonyl)-2-methylpiperazine.2HCl (H7) reduces the carbachol maximum and carbachol potency while increasing darifenacin affinity. |
1(0,0,0,1) | Details |
10679516 | Ito T, Kozawa O, Tanabe K, Niwa M, Matsuno H, Sakai N, Ito H, Kato K, Uematsu T: p38 MAP kinase is required for -stimulated HSP27 induction in aortic smooth muscle cells. Hypertension. 2000 Feb;35(2):673-8. We previously showed that arginine vasopressin (AVP) stimulates heat shock protein 27 (HSP27) induction through protein kinase C activation in aortic smooth muscle A10 cells. |
1(0,0,0,1) | Details |
9055074 | Neiman AM, Mhaiskar V, Manus V, Galibert F, Dean N: Saccharomyces cerevisiae HOC1, a suppressor of pkc1, encodes a putative glycosyltransferase. Genetics. 1997 Mar;145(3):637-45. The Saccharomyces cerevisiae gene PKC1 encodes a protein kinase C isozyme that regulates cell wall synthesis. The HOC1 gene (Homologous to OCH1) is predicted to encode a type II integral membrane protein that strongly resembles Och 1p, an alpha-1,6-mannosyltransferase. |
1(0,0,0,1) | Details |
19961846 | Nakamura K, Yokotani K: Presynaptic BK type Ca (2+)-activated K (+) channels are involved in prostanoid TP receptor-mediated inhibition of release from the rat gastric sympathetic nerves. Eur J Pharmacol. 2010 Mar 10;629(1-3):111-7. Epub 2009 Dec 2. Prostanoid TP receptor has been shown to activate phospholipase C (PLC), which catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to inositol 1,4,5- (IP (3)) and diacylglycerol; IP (3) triggers the release of Ca (2+) from intracellular stores and diacylglycerol activates protein kinase C. |
1(0,0,0,1) | Details |