Protein Information

Name glutathione S transferase
Synonyms GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2…

Compound Information

Name fenclorim
CAS 4,6-dichloro-2-phenylpyrimidine

Reference List

PubMed Abstract RScore(About this table)
20183093 Scarponi L, Del Buono D: Festuca arundinacea, glutathione S-transferase and herbicide safeners: a preliminary case study to reduce herbicidal pollution. J Environ Sci Health B. 2009 Nov;44(8):805-9.

The expression of glutathione S-transferase (GST) activity in Festuca arundinacea was investigated in response to the following herbicide safeners: benoxacor, cloquintocet-mexyl, fenchlorazol-ethyl, fenclorim, fluxofenim and oxabetrinil.
7(0,0,1,2) Details
16835885 Scarponi L, Quagliarini E, Del Buono D: Induction of wheat and maize glutathione S-transferase by some herbicide safeners and their effect on enzyme activity against butachlor and terbuthylazine. Pest Manag Sci. 2006 Oct;62(10):927-32.

The expression of glutathione S-transferase (GST) activity in wheat and maize shoots was investigated in response to treatments with the herbicide safeners benoxacor, cloquintocet-mexyl, fenchlorazole-ethyl, fenclorim, fluxofenim and oxabetrinil.
7(0,0,1,2) Details
18522943 Brazier-Hicks M, Evans KM, Cunningham OD, Hodgson DR, Steel PG, Edwards R: Catabolism of glutathione conjugates in Arabidopsis thaliana. J Biol Chem. 2008 Jul 25;283(30):21102-12. Epub 2008 Jun 3.

The safener fenclorim (4,6-dichloro-2-phenylpyrimidine) increases tolerance to chloroacetanilide herbicides in rice by enhancing the expression of detoxifying glutathione S-transferases (GSTs).
6(0,0,1,1) Details
12428014 DeRidder BP, Dixon DP, Beussman DJ, Edwards R, Goldsbrough PB: Induction of glutathione S-transferases in Arabidopsis by herbicide safeners. Plant Physiol. 2002 Nov;130(3):1497-505.

Treatment of Arabidopsis seedlings growing in liquid medium with various safeners similarly resulted in enhanced GST activities toward a range of xenobiotics with benoxacor, fenclorim, and fluxofenim being the most effective.
2(0,0,0,2) Details
16361527 DeRidder BP, Goldsbrough PB: Organ-specific expression of glutathione S-transferases and the efficacy of herbicide safeners in Arabidopsis. Plant Physiol. 2006 Jan;140(1):167-75. Epub 2005 Dec 16.

Benoxacor, fenclorim, and fluxofenim did not protect Arabidopsis from herbicide injury but did induce RNA expression of the glutathione-conjugate transporters encoded by AtMRP1, AtMRP2, AtMRP3, and AtMRP4.
2(0,0,0,2) Details
15032821 Fukuda A, Okada Y, Suzui N, Fujiwara T, Yoneyama T, Hayashi H: Cloning and characterization of the gene for a phloem-specific glutathione S-transferase from rice leaves. Physiol Plant. 2004 Apr;120(4):595-602.

Although some plant GSTs are known to be induced by xenobiotics, the amount of RPP31 was not affected by treatments with an herbicide, pretilachlor, and/or its safener, fenclorim.
2(0,0,0,2) Details