| Name | gamma glutamylcysteine synthetase |
|---|---|
| Synonyms | GCLM; GCS light chain; GLCLR; Gamma ECS; Gamma glutamylcysteine synthetase; Gamma glutamylcysteine synthetase regulatory subunit; Glutamate cysteine ligase modifier subunit; Glutamate cysteine ligase regulatory subunit… |
| Name | ethoxyquin |
|---|---|
| CAS | 6-ethoxy-1,2-dihydro-2,2,4-trimethylquinoline |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 7482539 | Buetler TM, Gallagher EP, Wang C, Stahl DL, Hayes JD, Eaton DL: Induction of phase I and phase II drug-metabolizing enzyme mRNA, protein, and activity by BHA, ethoxyquin, and oltipraz. Toxicol Appl Pharmacol. 1995 Nov;135(1):45-57. In this study, rats were treated with the monofunctional inducers tert-butylated hydroxyanisole, ethoxyquin, and oltipraz to study the inducibility of individual glutathione S-transferase isozymes, (H):quinone oxidoreductase, gamma-glutamylcysteine synthetase, UDP-glucuronosyl transferase, and cytochrome P450 enzymes. |
7(0,0,1,2) | Details |
| 11023540 | Shepherd AG, Manson MM, Ball HW, McLellan LI: Regulation of rat glutamate-cysteine ligase (gamma-glutamylcysteine synthetase) subunits by chemopreventive agents and in aflatoxin B (1)-induced preneoplasia. Carcinogenesis. 2000 Oct;21(10):1827-34. Treatment with the synthetic antioxidant ethoxyquin or the classic inducer phenobarbital caused < 2-fold induction of GLCL activity in rat liver, which was not found to be significant. |
4(0,0,0,4) | Details |