Protein Information

Name caspase 3
Synonyms Apopain; CASP 3; CASP3; CPP 32; CPP32; CPP32B; Caspase 3; Caspase 3 precursor…

Compound Information

Name trichlorfon
CAS

Reference List

PubMed Abstract RScore(About this table)
19775726 Xu WN, Liu WB, Liu ZP: Trichlorfon-induced apoptosis in hepatocyte primary cultures of Carassius auratus gibelio. Chemosphere. 2009 Nov;77(7):895-901. Epub 2009 Sep 22.

Trichlorfon increased intracellular reactive oxygen species and malondialdehyde concentrations and caused cytochrome c release from mitochondria into the cytoplasm, leading to caspase-3 activation.
62(0,2,2,2) Details
19631781 Liu CY, Chang PA, Wu YJ: Trichlorfon induces apoptosis in SH-SY5Y neuroblastoma cells via the endoplasmic reticulum?. Chem Biol Interact. 2009 Sep 14;181(1):37-44. Epub 2009 Mar 20.

Percent apoptosis and activated caspase-3 and caspase-12 decreased in pre-treated cells compared to those treated with trichlorfon alone.
31(0,1,1,1) Details