Protein Information

Name glutathione S transferases
Synonyms GST class alpha 2; Gst2; GST class alpha; GST class alpha member 2; GST gamma; GSTA 2; GSTA2; GSTA2 2…

Compound Information

Name dicamba
CAS 3,6-dichloro-2-methoxybenzoic acid

Reference List

PubMed Abstract RScore(About this table)
18436336 Peixoto FP, Gomes-Laranjo J, Vicente JA, Madeira VM: Comparative effects of the herbicides dicamba, 2,4-D and paraquat on non-green potato tuber calli. J Plant Physiol. 2008 Jul 31;165(11):1125-33. Epub 2008 Apr 23.

Paraquat slightly inhibited glutathione S-transferase (GST), whereas 2,4-D and dicamba promoted significant activation.
31(0,1,1,1) Details
9580876 Holovska K, Lenartova V, Rosival I, Kicinkova M, Majerciakova A, Legath J: Antioxidant and detoxifying enzymes in the liver and kidney of pheasants after intoxication by herbicides MCPA and ANITEN I. J Biochem Mol Toxicol. 1998;12(4):235-44.


The activity of antioxidant and detoxifying enzymes, such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSHPx), glutathione reductase, glutathione-S-transferase (GST), the contents of thiobarbituric acid reactive substances, and the superoxide dismutase and glutathione-S-transferase isoenzyme patterns, were determined in the liver and kidney of pheasants after acute intoxication by herbicides MCPA and ANITEN I.
3(0,0,0,3) Details
9863012 Espandiari P, Glauert HP, Lee EY, Robertson LW: Promoting activity of the herbicide dicamba (2-methoxy-3, 6-dichlorobenzoic acid) in two stage hepatocarcinogenesis. Int J Oncol. 1999 Jan;14(1):79-84.

0(0,0,0,0) Details
1755024 Moody DE, Narloch BA, Shull LR, Hammock BD: The effect of structurally divergent herbicides on mouse liver xenobiotic-metabolizing enzymes (P-450-dependent mono-oxygenases, epoxide hydrolases and glutathione S-transferases) and carnitine acetyltransferase. Toxicol Lett. 1991 Dec;59(1-3):175-85.

Dicamba, at the dose employed, caused mortality and decreases in some of the enzymes monitored.
2(0,0,0,2) Details