Protein Information

Name Ho 1
Synonyms HMOX 1; HMOX1; HMOX1 protein; HO; HO 1; HO1; Heme oxygenase (Decycling) 1; Heme oxygenase (Decyclizing) 1…

Compound Information

Name MAA
CAS methylarsonic acid

Reference List

PubMed Abstract RScore(About this table)
2944474 Fisher PB, Hermo H Jr, Solowey WE, Dietrich MC, Edwalds GM, Weinstein IB, Langer JA, Pestka S, Giacomini P, Kusama M, et al.: Effect of recombinant human fibroblast interferon and mezerein on growth, differentiation, immune interferon binding and tumor associated antigen expression in human melanoma cells. Anticancer Res. 1986 Jul-Aug;6(4):765-74.


In the present study we have further analyzed this synergistic interaction and have also evaluated the effect of IFN-delta and MEZ, alone and in combination, on recombinant human gamma interferon (IFN-gamma) binding and Class I HLA and melanoma associated antigen (MAA) expression in the HO-1 human melanoma cell line.
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16323392 Wang YW, Lin HC: Recent advances in hepatopulmonary syndrome. . J Chin Med Assoc. 2005 Nov;68(11):500-5.


Other mediators such as endothelin-1 and the heme oxygenase-1/carbon monoxide system have recently been found to be important contributors.
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2624919 Guarini L, Temponi M, Edwalds GM, Vita JR, Fisher PB, Ferrone S: In vitro differentiation and antigenic changes in human melanoma cell lines. Cancer Immunol Immunother. 1989;30(5):262-8.


To determine whether these changes reflect the differential expression of HLA antigens and MAA by melanocytes at different stages of differentiation, we have studied the effect of the reversible induction of differentiation by fibroblast interferon (interferon beta) and/or 12-O-tetradecanoyl-phorbol 13-acetate (TPA) on the expression of HLA antigens and MAA by the melanoma cell lines DU-2, FO-1 and HO-1.
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