Protein Information

Name integrins
Synonyms Alpha 11 precursor; HsT18964; ITGA11; Integrin; Integrin alpha 11; Integrin alpha 11 precursor; MSTP018; HsT18964s…

Compound Information

Name MAA
CAS methylarsonic acid

Reference List

PubMed Abstract RScore(About this table)
7537256 Veiga SS, Chammas R, Cella N, Brentani RR: Glycosylation of beta-1 integrins in B16-F10 mouse melanoma cells as determinant of differential binding and acquisition of biological activity. Int J Cancer. 1995 May 4;61(3):420-4.

6(0,0,0,6) Details
11936878 Challier JC, Carbillon L, Kacemi A, Vervelle C, Bintein T, Galtier M, Espie MJ, Uzan S: Characterization of first trimester human fetal placental vessels using immunocytochemical markers. Cell Mol Biol (Noisy-le-grand). 2001;47 Online Pub:OL79-87.


A labelling was observed for antibodies against alpha3 and alpha5 integrins in these immature placental vessels suggesting cell-matrix interactions with specific domains of laminin or fibronectin.
2(0,0,0,2) Details
9790958 Maa MC, Leu TH: Vanadate-dependent FAK activation is accomplished by the sustained FAK Tyr-576/577 phosphorylation. Biochem Biophys Res Commun. 1998 Oct 9;251(1):344-9.


Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase implicated in cell-matrix interaction and integrin signaling.
1(0,0,0,1) Details
12773770 Bae DS, Handa RJ, Yang RS, Campain JA: Gene expression patterns as potential molecular biomarkers for malignant transformation in human keratinocytes treated with MNNG, arsenic, or a metal mixture. Toxicol Sci. 2003 Jul;74(1):32-42. Epub 2003 May 28.


These 16 genes, nine (IFN inducible protein 9-27, MAA A32, CCLB protein, integrin beta4, XRCC1, K8, K18, MT3, MAPKK6) of which were altered in a chemical-specific manner and seven (MIC1, bikunin, MTS1, BMP4, RAD23A, DOC2, vimentin) of which were commonly affected by the MNNG and As or mixture treatments, were examined for expression in detail by real-time RT-PCR.
1(0,0,0,1) Details
12370821 Leu TH, Maa MC: Tyr-863 phosphorylation enhances focal adhesion kinase autophosphorylation at Tyr-397. Oncogene. 2002 Oct 10;21(46):6992-7000.


This observation implies that integrin-mediated FAK Tyr-397 phosphorylation was also regulated through both FAK cis- and transphosphorylation mechanisms.
1(0,0,0,1) Details