| PubMed |
Abstract |
RScore(About this table) |
| 14985818 |
Jameson GN, Zhang J, Jameson RF, Linert W: Kinetic evidence that cysteine reacts with dopaminoquinone via reversible adduct formation to yield 5-cysteinyl-dopamine: an important precursor of neuromelanin. Org Biomol Chem. 2004 Mar 7;2(5):777-82. Epub 2004 Feb 11.
Equilibrium constants and first-order rate constants have been extracted from the data and the cys complex is found to be weaker than its maa analogue by an order of magnitude (K (cys)=(1.09 +/- 0.02 x 10 (-3); K (1,maa)=(7.45 +/- 0.11 x 10 (-3)). (Note that the possibility that cys also forms a bis-complex at much higher cys concentrations cannot be excluded.) The rates of decomposition differ markedly-the cys complex has the value k (cys)= 1830 +/- 50 s (-1) whereas the rate constant for the decomposition of the maa complex is k (maa)= 69.3 +/- 0.02 s (-1) and we attribute this difference to the effect of the positive charge carried by the amino-group on cys. |
81(1,1,1,1) |
Details |
| 17763780 |
Yang J, Zhu XL, Su QD, Cai JB, Hu Y, Gao Y: [Spectroscopy and XPS studies on molecular recognition of a molecularly imprinted cotinine-specific polymer]. Guang Pu Xue Yu Guang Pu Fen Xi. 2007 Jun;27(6):1152-5.
The stoichiometric mole ratio of COT-MAA complex is 1 : 2. |
1(0,0,0,1) |
Details |