PubMed |
Abstract |
RScore(About this table) |
17692467 |
Greer DA, Ivey S: Distinct N-glycan glycosylation of P-glycoprotein isolated from the human uterine sarcoma cell line MES-SA/Dx5. Biochim Biophys Acta. 2007 Sep;1770(9):1275-82. Epub 2007 Jul 19.
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2(0,0,0,2) |
Details |
7913658 |
Ramirez LH, Munck JN, Zhao Z, Bognel C, Ricard M, Ardouin P, Rougier P, Gouyette A: Verapamil-reversing concentrations induce blood flow changes that could counteract in vivo the MDR-1-modulating effects. Cancer. 1994 Aug 1;74(3):810-6.
BACKGROUND: Intraarterial hepatic (IAH) administration of verapamil should achieve mdr-1-reversing concentrations with reduced cardiac toxicity. |
2(0,0,0,2) |
Details |
16922593 |
: Trabectedin: Ecteinascidin 743, Ecteinascidin-743, ET 743, ET-743, NSC 684766. Drugs R D. 2006;7(5):317-28.
It also inhibits overexpression of the multidrug resistance-1 gene (MDR-1) coding for the P-glycoprotein that is a major factor responsible for cells developing resistance to cancer drugs. |
1(0,0,0,1) |
Details |