| Name | Tyrosinase |
|---|---|
| Synonyms | LB24 AB; Monophenol monooxygenase; OCA1A; OCAIA; SK29 AB; TYR; TYR protein; Tumor rejection antigen AB… |
| Name | MAA |
|---|---|
| CAS | methylarsonic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17912445 | Ulasov IV, Rivera AA, Nettelbeck DM, Rivera LB, Mathis JM, Sonabend AM, Tyler M, Wang M, Douglas JT, Lesniak MS: An oncolytic adenoviral vector carrying the tyrosinase promoter for glioma gene therapy. Int J Oncol. 2007 Nov;31(5):1177-85. |
8(0,0,0,8) | Details |
| 9118024 | Fishman P, Merimski O, Baharav E, Shoenfeld Y: Autoantibodies to tyrosinase: the bridge between melanoma and vitiligo. . Cancer. 1997 Apr 15;79(8):1461-4. |
6(0,0,0,6) | Details |
| 8541724 | Baharav E, Merimsky O, Altomonte M, Shoenfeld Y, Pavlovic M, Maio M, Ferrone S, Fishman P: Anti-tyrosinase antibodies participate in the immune response to vaccination with anti-idiotypic antibodies mimicking the high-molecular-weight melanoma-associated antigen. Melanoma Res. 1995 Oct;5(5):337-43. |
6(0,0,0,6) | Details |
| 15305155 | Murer K, Urosevic M, Willers J, Selvam P, Laine E, Burg G, Dummer R: Expression of Melan-A/MART-1 in primary melanoma cell cultures has prognostic implication in metastatic melanoma patients. Melanoma Res. 2004 Aug;14(4):257-62. In order to investigate whether the MAA expression detected on cell cultures established from melanoma patients might relate to the overall survival in these patients, we screened primary cell cultures derived from 37 melanoma metastases for the expression of five known MAA: Melan-A, tyrosinase, gp-100, MAGE-1 and MAGE-3 by polymerase chain reaction (PCR) and fluorescence-activated cell sorting (FACS). |
3(0,0,0,3) | Details |
| 15946236 | Urosevic M, Braun B, Willers J, Burg G, Dummer R: Expression of melanoma-associated antigens in melanoma cell cultures. Exp Dermatol. 2005 Jul;14(7):491-7. We investigated the expression of five MAA - Melan-A/MART-1, tyrosinase, gp100, MAGE-1 and MAGE-3 - by means of FACS analysis in 50 melanoma cell cultures and compared them to the cultures of human foreskin-derived melanocytes and melanoma cell line UKRV-Mel2. |
2(0,0,0,2) | Details |
| 9456433 | Cormier JN, Abati A, Fetsch P, Hijazi YM, Rosenberg SA, Marincola FM, Topalian SL: Comparative analysis of the in vivo expression of tyrosinase, MART-1/Melan-A, and gp100 in metastatic melanoma lesions: implications for immunotherapy. J Immunother. 1998 Jan;21(1):27-31. |
5(0,0,0,5) | Details |
| 19951123 | Stell AJ, Dobson JM, Scase TJ, Catchpole B: Evaluation of variants of melanoma-associated antigen genes and mRNA transcripts in melanomas of dogs. Am J Vet Res. 2009 Dec;70(12):1512-20. A PCR assay was performed by use of Melan-A, SILV, or tyrosinase-specific primers. |
4(0,0,0,4) | Details |
| 12755292 | Catchpole B, Gould SM, Kellett-Gregory LM, Dobson JM: Development of a multiple-marker polymerase chain reaction assay for detection of metastatic melanoma in lymph node aspirates of dogs. Am J Vet Res. 2003 May;64(5):544-9. The RT-PCR assay was performed by use of tyrosinase, Melan-A, gp100, tyrosinase-related protein 2 (TRP-2), or melanoma antigen-encoding gene B (MAGE-B)-specific primers. |
2(0,0,0,2) | Details |
| 19386352 | Meije CB, Swart GW, Lepoole C, Das PK, Van den Oord JJ: Antigenic profiles of individual-matched pairs of primary and melanoma metastases. Hum Pathol. 2009 Oct;40(10):1399-407. Epub 2009 Apr 22. A unique collection of individual-matched pairs of primary and melanoma metastases were studied immunohistochemically with a panel of 6 monoclonal antibodies directed to gp-100, pigmentation-associated antigen, tyrosinase-related protein, human leukocyte antigen DR, MAA-1, and MAA-2 (high molecular weight melanoma-associated antigens). |
2(0,0,0,2) | Details |
| 11023194 | Fujii S, Huang S, Fong TC, Ando D, Burrows F, Jolly DJ, Nemunaitis J, Hoon DS: Induction of melanoma-associated antigen systemic immunity upon intratumoral delivery of interferon-gamma retroviral vector in melanoma patients. Cancer Gene Ther. 2000 Sep;7(9):1220-30. Patients were assessed for immunoglobulin G antibody (Ab) responses to the melanoma-associated antigens (MAA) tyrosinase, gp100, TRP-2, and MAGE-A1 by affinity enzyme-linked immunosorbent assay. |
2(0,0,0,2) | Details |
| 10727983 | Meije CB, Mooi WJ, Le Poole IC, Van Muijen GN, Das PK: Micro-anatomy related antigen expression in melanocytic lesions. J Pathol. 2000 Apr;190(5):572-8. The in situ expression of antigens associated with melanosomes (gp-100), pigmentation (PAA), tyrosinase (TRP-1), melanoma (MAA-1/MAA-2), and HLA-DR was investigated immunohistochemically in frozen archival specimens of common acquired melanocytic naevi, in dysplastic melanocytic naevi, and in lymph node metastases of melanoma. |
1(0,0,0,1) | Details |
| 9764850 | Huang SK, Okamoto T, Morton DL, Hoon DS: Antibody responses to melanoma/melanocyte autoantigens in melanoma patients. J Invest Dermatol. 1998 Oct;111(4):662-7. To assess antibody responses to potential melanoma/melanocyte autoantigens, the open-reading frame sequences of tyrosinase, tyrosinase-related protein (TRP)-1, TRP-2, and melanoma-associated glycoprotein antigen family (gp100/pmel17) genes were cloned and expressed as recombinant proteins in E. coli. |
1(0,0,0,1) | Details |
| 9176405 | Chi DD, Merchant RE, Rand R, Conrad AJ, Garrison D, Turner R, Morton DL, Hoon DS: Molecular detection of tumor-associated antigens shared by human cutaneous melanomas and gliomas. Am J Pathol. 1997 Jun;150(6):2143-52. The MAAs studied included tyrosinase (Tyr), tyrosinase-related protein-1 and -2 (TRP-1 and TRP-2), gp100, human melanoma antigen-encoding genes 1 and 3 (MAGE-1 and MAGE-3), and melanotransferrin (p97). |
1(0,0,0,1) | Details |
| 10653598 | Castelli C, Rivoltini L, Andreola G, Carrabba M, Renkvist N, Parmiani G: T-cell recognition of melanoma-associated antigens. . J Cell Physiol. 2000 Mar;182(3):323-31. These antigens belong to three main groups: tumor-associated testis-specific antigens (e.g. , MAGE, BAGE, and GAGE); melanocyte differentiation antigens (e.g., tyrosinase, Melan-A/MART-1); and mutated or aberrantly expressed molecules (e.g, CDK4, MUM-1, beta-catenin). |
1(0,0,0,1) | Details |
| 18652234 | Moiseenko VM, Danilova AB, Danilov AO, Turkevich EA, Baldueva IA, Matsko DE: [An immunocytochemical investigation of antigen expression by skin melanoma cells cultured for vaccine production]. Vopr Onkol. 2008;54(3):303-14. As of now, several varieties of melanoma-associated antigens (MAA) have been identified: MART1/melan A, tyrosinase, MITF, gp100, members of MAGE family, S100, CD63 and CD146. |
1(0,0,0,1) | Details |
| 9102226 | Sarantou T, Chi DD, Garrison DA, Conrad AJ, Schmid P, Morton DL, Hoon DS: Melanoma-associated antigens as messenger RNA detection markers for melanoma. Cancer Res. 1997 Apr 1;57(7):1371-6. Melanoma cell lines, melanocytes (cultured), primary and metastatic malignant melanoma tissues, and blood from patients with American Joint Committee on Cancer stage I-IV melanoma were assessed for tyrosinase, tyrosinase-related proteins 1 and 2, Pmel 17, and MART-1/Melan-A. |
1(0,0,0,1) | Details |
| 9810766 | Zeuthen J, Dzhandzhugazyan K, Hansen MR, Kirkin AF: The immunogenic properties of human melanomas and melanoma-associated antigens recognized by cytotoxic T lymphocytes. Bratisl Lek Listy. 1998 Aug-Sep;99(8-9):426-34. These antigens belong to three main groups: tumor-associated testis-specific antigens (MAGE, BAGE, GAGE and PRAME), melanocyte differentiation antigens (tyrosinase, Melan-A/MART-1, gp100, TRP-1 and TRP-2) and mutated or aberrantly expressed antigens (MUM-1, CDK4, beta-catenin, gp100-in4, p15 and N-acetylglucosaminyltransferase V). |
1(0,0,0,1) | Details |
| 9828818 | Hatta N, Takata M, Takehara K, Ohara K: Polymerase chain reaction and immunohistochemistry frequently detect occult melanoma cells in regional lymph nodes of melanoma patients. J Clin Pathol. 1998 Aug;51(8):597-601. The nested PCR for tyrosinase should be used in future studies investigating the prognostic significance of such lymph node micrometastases. |
1(0,0,0,1) | Details |
| 9773250 | Merimsky O, Shoenfeld Y, Fishman P: The clinical significance of antityrosinase antibodies in melanoma and related hypopigmentary lesions. Clin Rev Allergy Immunol. 1998 Fall;16(3):227-36. The autoantigen is tyrosinase itself, the enzyme that participates in pigment formation by both melanocytes and melanoma cells Antityrosinase IgG antibodies were found to be present in high titers in sera of patients with vitiligo in comparison to patients with melanoma or healthy volunteers. |
1(0,0,0,1) | Details |