| Name | chemokine |
|---|---|
| Synonyms | CXCL12; Chemokine; Chemokine ligand 12; PBSF; Pre B cell growth stimulating factor; SCYB12; SDF 1 alpha; SDF 1 beta… |
| Name | MAA |
|---|---|
| CAS | methylarsonic acid |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15608611 | Duryee MJ, Klassen LW, Freeman TL, Willis MS, Tuma DJ, Thiele GM: Lipopolysaccharide is a cofactor for malondialdehyde- adduct-mediated cytokine/chemokine release by rat sinusoidal liver endothelial and Kupffer cells. Alcohol Clin Exp Res. 2004 Dec;28(12):1931-8. |
3(0,0,0,3) | Details |
| 11747982 | Kharbanda KK, Todero SL, Shubert KA, Sorrell MF, Tuma DJ: Malondialdehyde--protein adducts increase secretion of chemokines by rat hepatic stellate cells. Alcohol. 2001 Oct;25(2):123-8. |
3(0,0,0,3) | Details |
| 16202982 | Thiele GM, Duryee MJ, Freeman TL, Sorrell MF, Willis MS, Tuma DJ, Klassen LW: Rat sinusoidal liver endothelial cells (SECs) produce pro-fibrotic factors in response to adducts formed from the metabolites of Biochem Pharmacol. 2005 Nov 25;70(11):1593-600. Epub 2005 Oct 3. Previous studies with -associated malondialdehyde- (MAA)-modified proteins have demonstrated an increase in the expression of adhesion molecules, and the secretion of pro-inflammatory cytokines/chemokines by rat sinusoidal liver endothelial cells (SECs). |
1(0,0,0,1) | Details |
| 18310089 | Tang CH, Chuang JY, Fong YC, Maa MC, Way TD, Hung CH: Bone-derived SDF-1 stimulates IL-6 release via CXCR4, ERK and NF-kappaB pathways and promotes osteoclastogenesis in human oral cancer cells. Carcinogenesis. 2008 Aug;29(8):1483-92. Epub 2008 Feb 28. The chemokine stromal cell-derived factor-1 (SDF-1) is constitutively secreted by osteoblasts and plays a key role in homing of hematopoietic cells to the bone marrow. |
1(0,0,0,1) | Details |
| 11853706 | Kharbanda KK, Shubert KA, Wyatt TA, Sorrell MF, Tuma DJ: Effect of malondialdehyde--protein adducts on the protein kinase C-dependent secretion of urokinase-type plasminogen activator in hepatic stellate cells. Biochem Pharmacol. 2002 Feb 1;63(3):553-62. Previous studies from our laboratory have shown that malondialdehyde--protein adducts (MAA adducts) are formed in hepatocytes of -fed rats and directly influence the hepatic stellate cells (HSCs) to induce their secretion of chemokines and to up-regulate their expression of adhesion molecules. |
1(0,0,0,1) | Details |
| 18435575 | Fong YC, Maa MC, Tsai FJ, Chen WC, Lin JG, Jeng LB, Yang RS, Fu WM, Tang CH: Osteoblast-derived TGF-beta1 stimulates IL-8 release through AP-1 and NF-kappaB in human cancer cells. J Bone Miner Res. 2008 Jun;23(6):961-70. It has been reported that the chemokine interleukin (IL)-8 is a potent and direct activator of osteoclastic differentiation and bone resorption. |
1(0,0,0,1) | Details |