Protein Information

Name IgE
Synonyms IGHE; Ig epsilon chain C region; IgE; immunoglobulin heavy constant epsilon; Ig epsilon chain C regions; IgEs; immunoglobulin heavy constant epsilons

Compound Information

Name MAA
CAS methylarsonic acid

Reference List

PubMed Abstract RScore(About this table)
10213364 Andya JD, Maa YF, Costantino HR, Nguyen PA, Dasovich N, Sweeney TD, Hsu CC, Shire SJ: The effect of formulation excipients on protein stability and aerosol performance of spray-dried powders of a recombinant humanized anti-IgE monoclonal antibody. Pharm Res. 1999 Mar;16(3):350-8.

2(0,0,0,2) Details
9811498 Costantino HR, Andya JD, Nguyen PA, Dasovich N, Sweeney TD, Shire SJ, Hsu CC, Maa YF: Effect of mannitol crystallization on the stability and aerosol performance of a spray-dried pharmaceutical protein, recombinant humanized anti-IgE monoclonal antibody. J Pharm Sci. 1998 Nov;87(11):1406-11.

2(0,0,0,2) Details
18543185 Wang CH, Maa SH, Yang SH, Chen YL, Chen WC: [Development of an add-on module for the WHOQOL-BREF on patients with allergic rhinitis]. Hu Li Za Zhi. 2008 Jun;55(3):49-60.


The total score and the scores on the physiological and environmental subscales showed convergent validity with the score for IgE (r= -.317 - -.380, p < .01) and with the total score and the scores on the subscale of the allergic rhinitis symptom questionnaire (r= -.202 - -.360, p < .01).
2(0,0,0,2) Details
10100310 Maa YF, Nguyen PA, Sweeney T, Shire SJ, Hsu CC: Protein inhalation powders: spray drying vs spray freeze drying. Pharm Res. 1999 Feb;16(2):249-54.


Two recombinant therapeutic proteins currently used for treating respiratory tract-related diseases, deoxyribonuclase (rhDNase) and anti-IgE monoclonal antibody (anti-IgE MAb), were employed and formulated with different carbohydrate excipients.
1(0,0,0,1) Details
10099432 Maa YF, Nguyen PA, Sit K, Hsu CC: Spray-drying performance of a bench-top spray dryer for protein aerosol powder preparation. Biotechnol Bioeng. 1998 Nov 5;60(3):301-9.


A Buchi mini-spray dryer was used to prepare the powders of recombinant humanized anti-IgE antibody.
1(0,0,0,1) Details
9619788 Maa YF, Nguyen PA, Andya JD, Dasovich N, Sweeney TD, Shire SJ, Hsu CC: Effect of spray drying and subsequent processing conditions on residual moisture content and physical/biochemical stability of protein inhalation powders. Pharm Res. 1998 May;15(5):768-75.


METHODS: Excipient-free as well as mannitol-formulated powders of a humanized monoclonal antibody (anti-IgE) and recombinant human deoxyribonuclease (rhDNase) were prepared using a Buchi 190 model spray dryer.
1(0,0,0,1) Details