| Name | steroidogenic acute regulatory protein |
|---|---|
| Synonyms | Cholesterol trafficker; STAR; STARD 1; STARD1; Start domain containing protein 1; Steroidogenic acute regulator; Steroidogenic acute regulatory protein; Start domain containing protein 1s… |
| Name | lindane |
|---|---|
| CAS | (1α,2α,3β,4α,5α,6β)-1,2,3,4,5,6-hexachlorocyclohexane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10993823 | Walsh LP, Stocco DM: Effects of lindane on steroidogenesis and steroidogenic acute regulatory protein expression. Biol Reprod. 2000 Oct;63(4):1024-33. |
6(0,0,1,1) | Details |
| 18248869 | Saradha B, Vaithinathan S, Mathur PP: Single exposure to low dose of lindane causes transient decrease in testicular steroidogenesis in adult male Wistar rats. Toxicology. 2008 Feb 28;244(2-3):190-7. Epub 2007 Nov 22. To get more insight into the mechanism (s) involved in gonadal effect (s) of lindane, we sought to investigate whether treatment with lindane at a low dose would alter the levels of steroidogenic acute regulatory protein (StAR), androgen binding protein (ABP) and activities of steroidogenic enzymes (3beta-hydroxysteroid dehydrogenase and 17beta-hydroxysteroid dehydrogenase) in adult rat. |
31(0,1,1,1) | Details |
| 17080404 | Oskarsson A, Ulleras E, Plant KE, Hinson JP, Goldfarb PS: Steroidogenic gene expression in H295R cells and the human adrenal gland: adrenotoxic effects of lindane in vitro. J Appl Toxicol. 2006 Nov-Dec;26(6):484-92. It was demonstrated that lindane reduced secretion, downregulated the expression of a subset of the genes encoding steroidogenic enzymes and repressed transcriptional activation of the steroidogenic acute regulatory protein (StAR) gene promoter. |
81(1,1,1,1) | Details |