| Name | CD4 |
|---|---|
| Synonyms | CD4; CD4 antigen (p55); CD4 molecule; CD4mut; T cell antigen T4/LEU3; T cell surface glycoprotein CD4; T cell surface antigen T4/Leu 3; T cell surface glycoprotein CD4 precursor… |
| Name | sodium arsenite |
|---|---|
| CAS | sodium arsenenite |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16275621 | Tenorio EP, Saavedra R: Differential effect of sodium arsenite during the activation of human CD4+ and CD8+ T lymphocytes. Int Immunopharmacol. 2005 Dec;5(13-14):1853-69. Epub 2005 Jun 21. |
85(1,1,1,5) | Details |
| 18407307 | Soto-Pena GA, Vega L: Arsenic interferes with the signaling transduction pathway of T cell receptor activation by increasing basal and induced phosphorylation of Lck and Fyn in spleen cells. Toxicol Appl Pharmacol. 2008 Jul 15;230(2):216-26. Epub 2008 Mar 10. Intra-gastric exposure to arsenic (as sodium arsenite) for 30 days (1, 0.1, or 0.01 mg/kg/day), reduced the proportion of CD4+ cells and the CD4+/CD8+ ratio in the spleen, increasing the proportion of CD11b+ cells. |
81(1,1,1,1) | Details |
| 15147786 | Vega L, Montes de Oca P, Saavedra R, Ostrosky-Wegman P: Helper T cell subpopulations from women are more susceptible to the toxic effect of sodium arsenite in vitro. Toxicology. 2004 Jul 1;199(2-3):121-8. Arsenic susceptibility of lymphocyte subpopulations (T helper (Th), CD4+; T cytotoxic (Tc), CD8+) and whether arsenic effects are gender related are still to be determined. |
1(0,0,0,1) | Details |
| 17009048 | Conde P, Acosta-Saavedra LC, Goytia-Acevedo RC, Calderon-Aranda ES: Sodium arsenite-induced inhibition of cell proliferation is related to inhibition of IL-2 mRNA expression in mouse activated T cells. Arch Toxicol. 2007 Apr;81(4):251-9. Epub 2006 Sep 29. Arsenite also decreased early activation (surface CD69+ expression) in both CD4+ and CD8+, and decreased total CD8+ count without significantly affecting CD4+, supporting that the cellular immune response mediated by cytotoxic T cells is an arsenic target. |
1(0,0,0,1) | Details |
| 8228242 | Tamura Y, Tsuboi N, Sato N, Kikuchi K: 70 kDa heat shock cognate protein is a transformation-associated antigen and a possible target for the host's anti-tumor immunity. J Immunol. 1993 Nov 15;151(10):5516-24. The accumulated data indicated that the cell surface expression of Ag was clearly enhanced by several stressors, such as TNF, L-azetidine-2-carboxylic acid, and sodium arsenite. |
0(0,0,0,0) | Details |