Protein Information

Name interleukin 2
Synonyms Aldesleukin; IL 2; IL2; Interleukin 2; Interleukin 2 precursor; T cell growth factor; TCGF; lymphokine…

Compound Information

Name sodium arsenite
CAS sodium arsenenite

Reference List

PubMed Abstract RScore(About this table)
10319276 Vega L, Ostrosky-Wegman P, Fortoul TI, Diaz C, Madrid V, Saavedra R: Sodium arsenite reduces proliferation of human activated T-cells by inhibition of the secretion of interleukin-2. Immunopharmacol Immunotoxicol. 1999 May;21(2):203-20.
81(1,1,1,1) Details
20339924 Das S, Pan D, Bera AK, Rana T, Bhattacharya D, Bandyapadyay S, De S, Sreevatsava V, Bhattacharya S, Das SK, Bandyopadhayay S: Sodium arsenite mediated immuno-disruption through alteration of transcription profile of cytokines in chicken splenocytes under in vitro system. Mol Biol Rep. 2010 Mar 26.

Relative quantification of expression of IFNgamma and IL2 revealed that both genes were significantly down regulated (P < 0.001) at both concentrations at each time point. iNOS gene was rapidly down regulated in splenocytes at 24 h at the high doses of As treated splenocyte, a gradual decreasing trend at low doses.
1(0,0,0,1) Details
9504978 Savabieasfahani M, Lochmiller RL, Rafferty DP, Sinclair JA: Sensitivity of wild cotton rats (Sigmodon hispidus) to the immunotoxic effects of low-level arsenic exposure. Arch Environ Contam Toxicol. 1998 Apr;34(3):289-96.


We exposed adult male cotton rats (n = 36) to either 0 (controls), 5 (low dose), or 10 (high dose) ppm sodium arsenite in drinking water for 6 weeks.
0(0,0,0,0) Details