| Name | sodium channel (protein family or complex) |
|---|---|
| Synonyms | Sodium channel |
| Name | lindane |
|---|---|
| CAS | (1α,2α,3β,4α,5α,6β)-1,2,3,4,5,6-hexachlorocyclohexane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8841090 | Narahashi T: Neuronal ion channels as the target sites of insecticides. Pharmacol Toxicol. 1996 Jul;79(1):1-14. The insecticide-channel interactions that have been studied most extensively are pyrethroid actions on the voltage-gated sodium channel and cyclodiene/lindane actions on the GABAA receptor chloride channel complex. |
35(0,1,1,5) | Details |
| 1281937 | Narahashi T, Frey JM, Ginsburg KS, Roy ML: and -activated channels as the targets of pyrethroids and cyclodienes. Toxicol Lett. 1992 Dec;64-65 Spec No:429-36. The type I pyrethroid allethrin and the type II pyrethroid deltamethrin were both effective in prolonging the current in the TXX-resistant sodium channel but had only a small effect on the TTX-sensitive sodium channel. In contrast to the pyrethroids, lindane and the cyclodienes endrin, isobenzan, dieldrin and heptachlor-epoxide suppressed the -induced current. |
1(0,0,0,1) | Details |