Protein Information

Name AMPK
Synonyms 5' AMP activated protein kinase subunit beta 1; AMPK; 5' AMP activated protein kinase beta 1 subunit; AMP activated protein kinase beta subunit; AMP activated protein kinase beta 1 non catalytic subunit; AMPK beta 1 chain; AMPK beta1; AMPKb…

Compound Information

Name sodium arsenite
CAS sodium arsenenite

Reference List

PubMed Abstract RScore(About this table)
18505831 Chanda D, Kim SJ, Lee IK, Shong M, Choi HS: Sodium arsenite induces orphan nuclear receptor SHP gene expression via AMP-activated protein kinase to inhibit gluconeogenic enzyme gene expression. Am J Physiol Endocrinol Metab. 2008 Aug;295(2):E368-79. Epub 2008 May 27.

Sodium arsenite augments hepatic SHP mRNA levels in an AMP-activated protein kinase (AMPK)-dependent manner.
193(2,3,3,3) Details
16280415 LaRosa C, Downs SM: Stress stimulates AMP-activated protein kinase and meiotic resumption in mouse oocytes. Biol Reprod. 2006 Mar;74(3):585-92. Epub 2005 Nov 9.

Cumulus-cell enclosed oocytes (CEO) or denuded oocytes (DO) from immature, eCG-primed mice were cultured for 17-18 h in dbcAMP-containing medium plus increasing concentrations of the metabolic poison, sodium arsenite, or the free radical-generating agent, menadione.
The AMP-activated protein kinase (PRKA; formerly known as AMPK) inhibitors, compound C and araA, completely blocked the meiosis-stimulating effects of all the tested stresses.
1(0,0,0,1) Details