Protein Information

Name Acetylcholinesterase
Synonyms ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant…

Compound Information

Name alachlor
CAS

Reference List

PubMed Abstract RScore(About this table)
18026775 Jin-Clark Y, Anderson TD, Zhu KY: Effect of alachlor and metolachlor on toxicity of chlorpyrifos and major detoxification enzymes in the aquatic midge, Chironomus tentans (Diptera: Chironomidae). Arch Environ Contam Toxicol. 2008 May;54(4):645-52. Epub 2007 Nov 17.

Furthermore, alachlor and metolachlor at 1,000 microg/L reduced acetylcholinesterase (AChE) activity by 34.3% and 27.6%, respectively, in the treated midges.
81(1,1,1,1) Details
16966160 Binelli A, Ricciardi F, Riva C, Provini A: Integrated use of biomarkers and bioaccumulation data in Zebra mussel (Dreissena polymorpha) for site-specific quality assessment. Biomarkers. 2006 Sep-Oct;11(5):428-48.

In this study, several persistent organic pollutants -- 23 polychlorinated biphenyl (PCB) congeners, 11 polycyclic aromatic hydrocarbons (PAHs), six dichlorodiphenyltricholroethane (DDT) relatives, hexachlorobenzene (HCB), chlorpyrifos and its oxidized metabolite -- and some herbicides (lindane and the isomers alpha, beta, delta; terbutilazine; alachlor; metolachlor) were measured in the soft tissues of the freshwater mollusc Zebra mussel (Dreissena polymorpha) from 25 sampling sites in the Italian portions of the sub-alpine great lakes along with the measure of ethoxyresorufin dealkylation (EROD) and acetylcholinesterase (AChE) activity.
31(0,1,1,1) Details
16998629 Fernandez M, Rios JC, Jos A, Repetto G: Comparative cytotoxicity of alachlor on RTG-2 trout and SH-SY5Y human cells. Arch Environ Contam Toxicol. 2006 Nov;51(4):515-20. Epub 2006 Sep 5.

In addition, acetylcholinesterase activity (AChE) was quantified in SH-SY5Y cells.
2(0,0,0,2) Details