Protein Information

Name CGRP
Synonyms Alpha type CGRP; CT; CGRP; CALC 1; CALC1; CALCA; CGRP 1; CGRP I…

Compound Information

Name SMA
CAS sodium 2-chloroacetate

Reference List

PubMed Abstract RScore(About this table)
18163477 Szabo A, Czirjak L, Sandor Z, Helyes Z, Laszlo T, Elekes K, Czompoly T, Starr A, Brain S, Szolcsanyi J, Pinter E: Investigation of sensory neurogenic components in a bleomycin-induced scleroderma model using transient receptor potential vanilloid 1 receptor- and calcitonin gene-related peptide-knockout mice. Arthritis Rheum. 2008 Jan;58(1):292-301.

5(0,0,0,5) Details
19408727 Wang L, Tai NZ, Fan ZH: [Effect of botulinum toxin type A on the expression of substance P, calcitionin gene-related peptide, transforming growth factor beta-1 and alpha smooth muscle actin A in wound healing in rats]. Zhonghua Zheng Xing Wai Ke Za Zhi. 2009 Jan;25(1):50-3.


OBJECTIVE: To investigate the effect of botulinum toxin type A on the expression of substance P (SP), calcitionin gene-related peptide (CGRP), transforming growth factor beta-1 (TGF-beta1) and alpha smooth muscle actin A (alpha-SMA) in wound healing.
3(0,0,0,3) Details
18673438 Kamiyoshi A, Sakurai T, Ichikawa-Shindo Y, Iinuma N, Kawate H, Yoshizawa T, Koyama T, Muto S, Shindo T: Endogenous alpha-calcitonin gene-related peptide mitigates liver fibrosis in chronic hepatitis induced by repeated administration of concanavalin A. Liver Int. 2009 May;29(5):642-9. Epub 2008 Jul 30.

2(0,0,0,2) Details
19523990 Yang JH, Cai Y, Duan XH, Ma CG, Wang X, Tang CS, Qi YF: Intermedin 1-53 inhibits rat cardiac fibroblast activation induced by angiotensin II. Regul Pept. 2009 Nov 27;158(1-3):19-25. Epub 2009 Jun 11.


Moreover, IMD (1-53) (10 (-8) or 10 (-7) mol/l) exerted a 25% and 45% respective inhibition in [(3) H]-thymidine incorporation and 16% and 36% respective inhibition in [(3) H]-proline incorporation in rat CFs incubated with AngII, and the actions of IMD (1-53) could be blocked by CGRP (8-37) and ADM (22-52).
2(0,0,0,2) Details