Protein Information

Name CD105
Synonyms CD105; CD105 antigen; EDG; END; ENG; Endoglin; Endoglin precursor; HHT 1…

Compound Information

Name SMA
CAS sodium 2-chloroacetate

Reference List

PubMed Abstract RScore(About this table)
17822316 Raica M, Cimpean AM, Anghel A: Immunohistochemical expression of vascular endothelial growth factor (VEGF) does not correlate with microvessel density in renal cell carcinoma. Neoplasma. 2007;54(4):278-84.


MVD was separately calculated on slides stained with CD31 and CD105.
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19716681 Mueller CK, Lee SY, Schultze-Mosgau S: Characterization of interfacial reactions between connective tissue and allogenous implants used for subdermal soft tissue augmentation. Int J Oral Maxillofac Surg. 2009 Nov;38(11):1194-200. Epub 2009 Aug 28.


After 7 or 14 days, tissue specimens were obtained and analyzed for transforming growth factor (TGF)-beta1 and vascular endothelial growth factor (VEGF) by immunoblotting as well as alpha-smooth muscle actin (SMA)-and endoglin (CD105)-expression by immunohistochemistry.
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18590220 Zhu M, Gao JH, Lu F: [Cell biological study of cultured cells derived from the fattyoffluid portions of liposuction aspirates]. Zhonghua Zheng Xing Wai Ke Za Zhi. 2008 Mar;24(2):138-44.


CD29, CD44, CD34, which were the markers of mesenchymal stem cells, vWF, CD31, CD105, SMA were all expressed in ASCs.
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20185896 Griesche N, Luttmann W, Luttmann A, Stammermann T, Geiger H, Baer PC: A Simple Modification of the Separation Method Reduces Heterogeneity of Adipose-Derived Stem Cells. Cells Tissues Organs. 2010 Feb 24.

We tested different isolation methods: (1) the standard isolation method for ASCs based on plastic attachment, (2) the standard method with an initial washing step after 60 min of adherence and (3) immunomagnetic isolation by 4 typical markers (CD49a, CD90, CD105 and CD271).
Washing led to a significantly lower expression of desmin, smA and six2, and a higher expression of the stem cell markers nestin, oct-4 and sall-1, compared to standard isolated cells, while the immunomagnetically isolated cells showed no significant changes.
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18317352 Jockovich ME, Pina Y, Alegret A, Cebulla C, Feuer W, Murray TG: Heterogeneous tumor vasculature in retinoblastoma: implications for vessel targeting therapy. Retina. 2008 Mar;28(3 Suppl):S81-6.

Total microvessel density was detected by staining endothelial cells using a lectin from Bandeira simplicifolia; novel vasculature was detected with the endothelial cell marker endoglin (CD105).
Vessel maturation was assessed by pericyte recruitment, detected with alpha smooth muscle actin (alpha-sma).
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