Protein Information

Name thrombospondin 1
Synonyms THBS; TSP 1; TSP1; THBS 1; THBS1; TSP; Thrombospondin I; Thrombospondin 1 precursor…

Compound Information

Name SMA
CAS sodium 2-chloroacetate

Reference List

PubMed Abstract RScore(About this table)
18413367 Wu MP, Young MJ, Tzeng CC, Tzeng CR, Huang KF, Wu LW, Chou CY: A novel role of thrombospondin-1 in cervical carcinogenesis: inhibit stroma reaction by inhibiting activated fibroblasts from invading cancer. Carcinogenesis. 2008 Jun;29(6):1115-23. Epub 2008 Apr 15.

2(0,0,0,2) Details
20195829 Xie XS, Li FY, Liu HC, Deng Y, Li Z, Fan JM: LSKL, a peptide antagonist of thrombospondin-1, attenuates renal interstitial fibrosis in rats with unilateral ureteral obstruction. Arch Pharm Res. 2010 Feb;33(2):275-84. Epub 2010 Feb 24.

2(0,0,0,2) Details
18988308 Xie XS, Yang M, Liu HC, Zuo C, Li Z, Deng Y, Fan JM: Influence of ginsenoside Rg1, a panaxatriol saponin from Panax notoginseng, on renal fibrosis in rats with unilateral ureteral obstruction. J Zhejiang Univ Sci B. 2008 Nov;9(11):885-94.


Moreover, ginsenoside Rg1 substantially suppressed the expression of thrombospondin-1 (TSP-1), a cytokine which can promote the transcription of TGF-beta1 mRNA and the activation of latent TGF-beta1.
1(0,0,0,1) Details