Name | myocardin |
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Synonyms | MYCD; MYOCD; Myocardin; Myocardins |
Name | SMA |
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CAS | sodium 2-chloroacetate |
PubMed | Abstract | RScore(About this table) | |
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18154735 | Sebe A, Masszi A, Zulys M, Yeung T, Speight P, Rotstein OD, Nakano H, Mucsi I, Szaszi K, Kapus A: Rac, PAK and p38 regulate cell contact-dependent nuclear translocation of myocardin-related transcription factor. FEBS Lett. 2008 Jan 23;582(2):291-8. Epub 2007 Dec 27. Contact disruption by low-Ca (2+) medium (LCM) activated Rac, PAK and p38 MAPK, and triggered the nuclear accumulation of myocardin-related transcription factor (MRTF), an inducer of the SMA promoter. |
32(0,1,1,2) | Details |
19094487 | Li Y, Qu ZL, Huang G, Meng H, Yu J, Ruan QR: [Expression of myocardin in differentiation of bone marrow-derived mesenchymal stem cells to smooth muscle cells]. Zhonghua Bing Li Xue Za Zhi. 2008 Oct;37(10):680-6. |
9(0,0,0,9) | Details |
20016221 | Sebe A, Erdei Z, Varga K, Bodor C, Mucsi I, Rosivall L: Cdc42 regulates myocardin-related transcription factor nuclear shuttling and alpha-smooth muscle actin promoter activity during renal tubular epithelial-mesenchymal transition. Nephron Exp Nephrol. 2010;114(3):e117-25. Epub 2009 Dec 16. |
2(0,0,0,2) | Details |
19015263 | Jin L, Yoshida T, Ho R, Owens GK, Somlyo AV: The actin-associated protein Palladin is required for development of normal contractile properties of smooth muscle cells derived from embryoid bodies. J Biol Chem. 2009 Jan 23;284(4):2121-30. Epub 2008 Nov 17. The filamentous (F) to globular (G) actin ratio, known to regulate myocardin family transcription factors, was also decreased. |
1(0,0,0,1) | Details |
19608972 | Grabski AD, Shimizu T, Deou J, Mahoney WM Jr, Reidy MA, Daum G: Sphingosine-1-phosphate receptor-2 regulates expression of smooth muscle alpha-actin after arterial injury. Arterioscler Thromb Vasc Biol. 2009 Oct;29(10):1644-50. Epub 2009 Jul 16. At various time points after injury, expression of multiple SMC differentiation genes, myocardin, and S1P receptors (S1P1R, S1P2R, and S1P3R) was measured by quantitative PCR. |
1(0,0,0,1) | Details |
18655827 | Kim YM, Jeon ES, Kim MR, Lee JS, Kim JH: Bradykinin-induced expression of alpha-smooth muscle actin in human mesenchymal stem cells. Cell Signal. 2008 Oct;20(10):1882-9. Epub 2008 Jul 4. This BK-induced alpha-SMA expression was abrogated by small interfering RNA (siRNA)-mediated depletion of endogenous myocardin, a transcription factor involved in smooth muscle differentiation. |
1(0,0,0,1) | Details |
20177148 | Jeon ES, Heo SC, Lee IH, Choi YJ, Park JH, Choi KU, Park DY, Suh DS, Yoon MS, Kim JH: Ovarian Cancer-Derived Lysophosphatidic Acid Stimulates Secretion of VEGF and SDF-1a from Human Mesenchymal Stem Cells. Exp Mol Med. 2010 Feb 22. LPA induced expression of myocardin and myocardin-related transcription factor-A, transcription factors involved in smooth muscle differentiation, in hASCs. |
1(0,0,0,1) | Details |
20123992 | Masszi A, Speight P, Charbonney E, Lodyga M, Nakano H, Szaszi K, Kapus A: Fate-determining mechanisms in epithelial-myofibroblast transition: major inhibitory role for Smad3. J Cell Biol. 2010 Feb 8;188(3):383-99. Epub 2010 Feb 1. We have shown previously that both injury to intercellular contacts and transforming growth factor beta (TGF-beta) are indispensable for SMA expression (two-hit model) and that contact disruption induces nuclear translocation of myocardin-related transcription factor (MRTF). |
1(0,0,0,1) | Details |
20096071 | Yu J, Li Y, Li M, Qu Z, Ruan Q: Oxidized low density lipoprotein-induced transdifferentiation of bone marrow-derived smooth muscle-like cells into foam-like cells in vitro. Int J Exp Pathol. 2010 Feb;91(1):24-33. When SMLCs were incubated with different concentrations of ox-LDL, LOX-1 expression on the surface of SMLCs gradually increased with the increase of the ox-LDL concentration, but myocardin and SMC-specific marker genes decreased, accordingly. |
1(0,0,0,1) | Details |