| Name | beta actin |
|---|---|
| Synonyms | ACTB; Actin beta; Beta actin; Beta cytoskeletal actin; PS1TP5BP1; Actin betas; Beta actins; Beta cytoskeletal actins |
| Name | SMA |
|---|---|
| CAS | sodium 2-chloroacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19551523 | Hirschfeld J, Maurer J, Jung D, Kwiecinski M, Khimji AK, Dienes HP, Fries JW, Odenthal M: Targeting myofibroblasts in model systems of fibrosis by an artificial alpha-smooth muscle-actin promoter hybrid. Mol Biotechnol. 2009 Oct;43(2):121-9. Epub 2009 Jun 24. An artificial promoter containing the -702 bp regulatory sequence of the alpha-smooth muscle actin (SMA) gene linked to the first intron enhancer sequence of the beta-actin gene and the beta-globin intron-exon junction was constructed and tested for myofibroblast-dependent gene expression using the green fluorescent protein as a reporter. |
84(1,1,1,4) | Details |
| 17998247 | Tadesse H, Deschenes-Furry J, Boisvenue S, Cote J: KH-type splicing regulatory protein interacts with survival motor neuron protein and is misregulated in spinal muscular atrophy. Hum Mol Genet. 2008 Feb 15;17(4):506-24. Epub 2007 Nov 12. KH-type splicing regulatory protein (KSRP) is closely related to chick zipcode-binding protein 2 and rat MARTA1, which are involved in neuronal transport and localization of beta-actin and microtubule-associated protein 2 mRNAs, respectively. |
1(0,0,0,1) | Details |
| 18317806 | Maeda T, Hashitani S, Zushi Y, Segawa E, Tanaka N, Sakurai K, Urade M: Establishment of a nude mouse transplantable model of a human malignant fibrous histiocytoma of the mandible with high metastatic potential to the lung. J Cancer Res Clin Oncol. 2008 Sep;134(9):1005-11. Epub 2008 Mar 4. RT-PCR analysis demonstrated human beta-actin in this tumor line, indicating the human origin. |
1(0,0,0,1) | Details |
| 20188701 | Todd AG, Shaw DJ, Morse R, Stebbings H, Young PJ: SMN and the Gemin proteins form sub-complexes that localise to both stationary and dynamic neurite granules. Biochem Biophys Res Commun. 2010 Mar 26;394(1):211-6. Epub 2010 Feb 25. SMN has been linked to the axonal transport of beta-actin mRNA, a breakdown in which could trigger disease onset. |
1(0,0,0,1) | Details |
| 17923533 | Jablonka S, Beck M, Lechner BD, Mayer C, Sendtner M: Defective Ca2+ channel clustering in axon terminals disturbs excitability in motoneurons in spinal muscular atrophy. J Cell Biol. 2007 Oct 8;179(1):139-49. These defects correlate with reduced beta-actin messenger RNA and protein levels in distal axons. |
1(0,0,0,1) | Details |
| 18629520 | Simic G: Pathogenesis of proximal autosomal recessive spinal muscular atrophy. . Acta Neuropathol. 2008 Sep;116(3):223-34. Epub 2008 Jul 16. In this review, new findings regarding the dual cellular role of the SMN protein (translocation of beta-actin to axonal growth cones and snRNP biogenesis/pre-mRNA splicing) were integrated with recent data obtained by detailed neuropathological examination of SMA and control subjects. |
1(0,0,0,1) | Details |