| Name | CD117 |
|---|---|
| Synonyms | C Kit; CD117; CD117 antigen; KIT; KIT oncogene Mast cell growth factor receptor; KIT protein; Mast/stem cell growth factor receptor; Mast/stem cell growth factor receptor precursor… |
| Name | SMA |
|---|---|
| CAS | sodium 2-chloroacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18036812 | Yamate J, Ogata K, Yuasa T, Kuwamura M, Takenaka S, Kumagai D, Itoh K, LaMarre J: Adipogenic, osteogenic and myofibrogenic differentiations of a rat malignant fibrous histiocytoma (MFH)-derived cell line, and a relationship of MFH cells with embryonal mesenchymal, perivascular and bone marrow stem cells. Eur J Cancer. 2007 Dec;43(18):2747-56. In rat tissues, A3 labelled with immature mesenchymal and perivascular cells in foetuses and neonates, and with marrow stem cells in adults. c-kit mRNA expression was seen in bone marrows and MT-9. |
1(0,0,0,1) | Details |
| 19319643 | Dell'Avanzato R, Carboni F, Palmieri MB, Palmirotta R, Guadagni F, Pippa G, Santeusanio G, Antimi M, Lopez M, Carlini M: Laparoscopic resection of sporadic synchronous gastric and jejunal gastrointestinal stromal tumors: report of a case. Surg Today. 2009;39(4):335-9. Epub 2009 Mar 25. Immunohistochemical analysis revealed that both lesions were KIT (CD117)-positive, but that the gastric lesion was CD34-positive, whereas the jejunal one was Vimentin-, S-100-, and SMA-positive. |
1(0,0,0,1) | Details |
| 17571460 | Ke Q, Erbolat, Zhang HY, Bu H, Li S, Shi DN, Yang GH, Chen HJ, Wei B: Clinicopathologic features of pleomorphic hyalinizing angiectatic tumor of soft parts. Chin Med J. 2007 May 20;120(10):876-81. Immunohistochemical stains for vimentin, S-100 protein, CD34, CD31, CD99, VEGF, desmin, CD117, alpha-SMA, and MIB-1 were performed with the Envision system. |
1(0,0,0,1) | Details |
| 19255573 | Mansuroglu T, Ramadori P, Dudas J, Malik I, Hammerich K, Fuzesi L, Ramadori G: Expression of stem cell factor and its receptor c-Kit during the development of intrahepatic cholangiocarcinoma. Lab Invest. 2009 May;89(5):562-74. Epub 2009 Mar 2. |
9(0,0,0,9) | Details |
| 18359707 | Liu J, Liu YH: [Expression of CD117, CD34, SMA, S-100 protein, Vim and desmin in patients with gastrointestinal stromal tumors]. Nan Fang Yi Ke Da Xue Xue Bao. 2008 Mar;28(3):438-40. |
5(0,0,0,5) | Details |
| 20123583 | Chou CC, Chou MJ, Tzen CY: Prediction of KIT mutation in gastrointestinal stromal tumors by the immunoprofile of the tumor cells. J Formos Med Assoc. 2010 Jan;109(1):25-31. METHODS: One hundred and forty-nine GIST were subjected to mutation analysis for KIT and immunohistochemical analysis for the expression of CD117, CD34, alpha-smooth muscle actin (SMA), and S100 protein. |
4(0,0,0,4) | Details |
| 17883045 | Paul PC, Chakraborty J, Kundu D, Sarkar R: -intestinal stromal tumour--role of CD117 in diagnosis and management. Indian J Pathol Microbiol. 2007 Apr;50(2):279-83. |
4(0,0,0,4) | Details |
| 19175711 | Ramirez-Amador V, Martinez-Mata G, Gonzalez-Ramirez I, Anaya-Saavedra G, de Almeida OP: Clinical, histological and immunohistochemical findings in oral Kaposi's sarcoma in a series of Mexican AIDS patients. J Oral Pathol Med. 2009 Apr;38(4):328-33. Epub 2009 Jan 23. Immunohistochemical studies were performed for vimentin, alpha SMA, desmin, C-kit, CD34, D2-40 and LANA-1 [human herpesvirus-8 (HHV-8)]. |
3(0,0,0,3) | Details |
| 17991328 | Huang KH, Liu JH, Wang LY, Wang LY, Li CQ, Zhu ZH, Li HG: [Endoscopic, clinicopathologic and immunohistochemical features of gastric stromal tumor]. Ai Zheng. 2007 Nov;26(11):1252-6. The expression of CD117, CD34, smooth muscle actin (SMA), Desmin and S-100 were detected by immunohistochemistry. |
3(0,0,0,3) | Details |
| 18505417 | Ji F, Wang ZW, Wang LJ, Ning JW, Xu GQ: Clinicopathological characteristics of gastrointestinal mesenchymal tumors and diagnostic value of endoscopic ultrasonography. J Gastroenterol Hepatol. 2008 Aug;23(8 Pt 2):e318-24. Epub 2008 May 26. The expression of CD117, CD34, smooth muscle actin (SMA), S-100, and Ki-67 were detected using immunohistochemistry. |
3(0,0,0,3) | Details |
| 20091704 | Mohammadi A, Rosa M, Masood S: The use of fine-needle aspiration biopsy samples for the assessment of basal phenotype in triple negative breast cancer patients: A correlative study. Diagn Cytopathol. 2010 Jan 20. Tissue microarray blocks were prepared and stained with six biomarkers (CK5/6, p63, SMA, EGFR, C-Kit, and p53). |
3(0,0,0,3) | Details |
| 18949416 | Tai WC, Chuah SK, Lin JW, Chen HH, Huang HY, Kuo CM, Yi LN, Lee CM, Changchien CS, Hu TH: Colorectal mesenchymal tumors - from smooth muscle tumors to stromal tumors. Oncol Rep. 2008 Nov;20(5):1157-64. Forty of 53 GIST were initially diagnosed as smooth muscle tumors and re-diagnosed as CD117 (+) GIST. |
2(0,0,0,2) | Details |
| 18087173 | El Kossi MM, Haylor JL, Johnson TS, El Nahas AM: Stem cell factor in a rat model of serum nephrotoxic nephritis. . Nephron Exp Nephrol. 2008;108(1):e1-e10. Epub 2007 Dec 17. Rats' kidneys were immunostained for ED1 as marker of inflammation, CD34, SCF, c-kit, mast cell tryptase and markers of fibrosis; collagens III and IV and alpha-SMA. |
2(0,0,0,2) | Details |
| 17852882 | Dong C, Jun-Hui C, Xiao-Jun Y, Mei K, Bo W, Chen-Fe J, Wei-Li Y: Gastrointestinal stromal tumors of the rectum: Clinical, pathologic, immunohistochemical characteristics and prognostic analysis. Scand J Gastroenterol. 2007 Oct;42(10):1221-9. Positive expression of CD117, CD34, SMA and S-100 was found in 28, 28, 7 and 3 patients, respectively. |
2(0,0,0,2) | Details |
| 19717420 | Bearzi C, Leri A, Lo Monaco F, Rota M, Gonzalez A, Hosoda T, Pepe M, Qanud K, Ojaimi C, Bardelli S, D'Amario D, D'Alessandro DA, Michler RE, Dimmeler S, Zeiher AM, Urbanek K, Hintze TH, Kajstura J, Anversa P: Identification of a coronary vascular progenitor cell in the human heart. . Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15885-90. Epub 2009 Aug 27. The expression of vascular endothelial growth-factor receptor 2 (KDR) was used, together with the stem cell antigen c-kit, to isolate and expand a resident coronary vascular progenitor cell (VPC) from human myocardial samples. |
2(0,0,0,2) | Details |
| 18261305 | Luo DL, Liu YH, Zhuang HG, Luo XL: [Tumors showing perivascular epithelioid cell differentiation: a clinicopathologic study of 39 cases]. Zhonghua Yi Xue Za Zhi. 2007 Nov 6;87(41):2909-13. Immunohistochemistry (HIC) was used to detect the expression of pan-cytokeratin (CK), S-100 protein, smooth muscle actin (SMA), desmin, vimentin, HMB45, Melan-A, microphthalmia transcription factor (MiTF), CD117, and CD34 in the specimens of the tumors obtained during operation. |
2(0,0,0,2) | Details |
| 20021609 | Kwon MJ, Nam ES, Cho SJ, Park HR, Shin HS, Park JH, Park CH, Lee WJ: Comparison of tissue microarray and full section in immunohistochemistry of gastrointestinal stromal tumors. Pathol Int. 2009 Dec;59(12):851-6. Six primary antibody markers (c-Kit, CD34, smooth muscle actin (SMA), S-100, p53, and Ki-67) were used with the TMA technique to analyze 0.6 mm, 2 mm, and 3 mm punch cores of GIST samples from 67 patients. |
2(0,0,0,2) | Details |
| 18446631 | Pauli J, Gundelach R, Vanelli-Rees A, Rees G, Campbell C, Dubey S, Perry C: Juvenile nasopharyngeal angiofibroma: an immunohistochemical characterisation of the stromal cell. Pathology. 2008 Jun;40(4):396-400. Recently, expression of several growth factors and oncoproteins including CD117 (c-kit) in the stromal cells has been demonstrated. |
2(0,0,0,2) | Details |
| 18070470 | Chen XC, Shan HW, Qu HL, Ge JB, Ge ZP: [Bone marrow mesenchymal stem cell transplantation aggravates postangioplasty aortic restenosis in rats]. Zhonghua Xin Xue Guan Bing Za Zhi. 2007 Sep;35(9):802-6. Expressions of c-kit, proliferating cell nuclear antigen (PCNA), smooth muscle alpha-actin (alpha-SMA) in aorta were determined by immunocytochemistry using related antibodies. |
2(0,0,0,2) | Details |
| 20025524 | Spitalieri P, Cortese G, Pietropolli A, Filareto A, Dolci S, Klinger FG, Giardina E, Di Cesare S, Bernardini L, Lauro D, Scaldaferri HL, Citro G, Novelli G, De Felici M, Sangiuolo F: Identification of multipotent cytotrophoblast cells from human first trimester chorionic villi. Cloning Stem Cells. 2009 Dec;11(4):535-56. In this article we used immunohistochemistry and FACS analyses to show that cells expressing markers typical of human stem cells such as SSEA4, OCT-4, ALP, and CD117 are present within the cytotrophoblastic tissue of human fetal chorionic villus samples (CVSs). |
1(0,0,0,1) | Details |
| 19863672 | Orzechowska BU, Manoharan M, Sprague J, Estep RD, Axthelm MK, Wong SW: Viral interleukin-6 encoded by rhesus macaque rhadinovirus is associated with lymphoproliferative disorder (LPD). J Med Primatol. 2009 Oct;38 Suppl 1:2-7. Similarly to KS, RF lesion is positive for vimentin, CD117 (c-kit), and smooth muscle actin (SMA) and contains T cell, B cell and monocytes/macrophage infiltrates. |
1(0,0,0,1) | Details |
| 18664259 | Yoshimura N, Ohara H, Miyabe K, Ban T, Sano H, Naitoh I, Hayashi K, Ando T, Nakazawa T, Joh T: A case of gastrointestinal stromal tumor with spontaneous rupture in the greater omentum. Int Semin Surg Oncol. 2008 Jul 29;5:19. Histologically, the tumor was composed of spindle cells, and was positive for c-KIT (CD117), slightly positive for alpha-smooth muscle actin (SMA), and S-100 protein positive. |
1(0,0,0,1) | Details |
| 18689869 | Tabatabai G, Herrmann C, von Kurthy G, Mittelbronn M, Grau S, Frank B, Mohle R, Weller M, Wick W: VEGF-dependent induction of CD62E on endothelial cells mediates glioma tropism of adult haematopoietic progenitor cells. Brain. 2008 Oct;131(Pt 10):2579-95. Epub 2008 Aug 9. Neutralizing antibodies to CD62E strongly reduced the homing of lin (-) Sca-1 (+) c-kit (+) cells to orthotopic SMA-560 gliomas in vivo. |
1(0,0,0,1) | Details |
| 19145686 | Zissis D, Zizi-Serbetzoglou A, Glava C, Grammatoglou X, Katsamagkou E, Nikolaidou ME, Vasilakaki T: Glomus tumor of the stomach: a case report. J BUON. 2008 Oct-Dec;13(4):581-4. Biopsies taken from the lesion showed morphological and immunohistochemical [positivity for alphasmooth muscle actin (alpha-SMA) and vimentin, negativity for CD34, CD117, chromogranin, synaptophysin, desmin and S-100 protein] characteristics attributable to glomus tumor. |
1(0,0,0,1) | Details |
| 19886076 | Zurac S, Tudose I, Micu G, Bastian A, Gamada E, Staniceanu F, Popp C, Simeanu D, Haidar A: Rectal leiomyoma--report of two cases originating in muscularis mucosae. Rom J Intern Med. 2009;47(1):97-100. These tumors have a different clinical course than gastrointestinal stromal tumors; since morphologic appearance is sometimes confusing, CD117 staining is mandatory for an accurate diagnostic. |
1(0,0,0,1) | Details |
| 19614993 | Hafezi-Bakhtiari S, Al-Habeeb A, Ghazarian D: Benign mixed tumor of the skin, hypercellular variant: a case report. J Cutan Pathol. 2009 Jul 10. Immunohistochemical studies revealed positive immunoreactivity for EMA, CEA, CD117, HWMK, LWMK, CK7, Androgen receptor and S100 in the ductal (epithelial) cells and positive immunereactivity for calponin, SMA, CK 5/6 and p63 in the myoepithelial component. |
1(0,0,0,1) | Details |
| 19852056 | Zimmerlin L, Donnenberg VS, Pfeifer ME, Meyer EM, Peault B, Rubin JP, Donnenberg AD: Stromal vascular progenitors in adult human adipose tissue. . Cytometry A. 2010 Jan;77(1):22-30. These markers were used in multiparameter flow cytometry in conjunction with stem/progenitor markers (CD90 and CD117) to further characterize stromal vascular fraction (SVF) subpopulations. |
1(0,0,0,1) | Details |
| 17708776 | Efstathios P, Athanasios P, Papaconstantinou I, Alexandros P, Frangisca S, Sotirios G, Evangelos F, Athanasios G: Coexistence of gastrointestinal stromal tumor (GIST) and colorectal adenocarcinoma: A case report. World J Surg Oncol. 2007 Aug 21;5:96. Immunohistochemical examination revealed the concurrence of histologically proved GIST (strongly positive staining for c-kit, vimentin, SMA, and focal positive in S-100, while CD-34 was negative) and Dukes Stage C, (T3, N3, M0 according the TNM staging classification of colorectal cancer). |
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| 19926495 | Schnee S, Sass K, Moellmer H, Hohenfellner R, Spanel-Borowski K: Heterogeneity of atherosclerosis in mesenteric arteries and outgrowth remodeling. Cardiovasc Pathol. 2009 Nov 17. During atherosclerotic progression, a stable fraction of leukocytes represented mast cells (6%) and CD117-positive cells as potential progenitor cells (1%). |
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| 19855377 | Thike AA, Cheok PY, Jara-Lazaro AR, Tan B, Tan P, Tan PH: Triple-negative breast cancer: clinicopathological characteristics and relationship with basal-like breast cancer. Mod Pathol. 2010 Jan;23(1):123-33. Epub 2009 Oct 23. Using a set of 61 invasive breast cancers earlier profiled into molecular subtypes with expression arrays, we defined specificity and sensitivity values for different immunohistochemical panels of basal keratins (CK5/6, CK14, CK17, 34 beta E12), CD117, EGFR, p63 and SMA in defining basal-like breast cancer. |
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| 18177424 | Ruger BM, Breuss J, Hollemann D, Yanagida G, Fischer MB, Mosberger I, Chott A, Lang I, Davis PF, Hocker P, Dettke M: Vascular morphogenesis by adult bone marrow progenitor cells in three-dimensional fibrin matrices. Differentiation. 2008 Sep;76(7):772-83. Epub 2008 Jan 3. The culture of unselected BMMNC in 3D fibrin matrices led to the formation of cell clusters expressing the endothelial progenitor cell (EPC) markers CD133, CD34, vascular endothelial growth factor receptor (VEGFR)-2, and c-kit, with stellar shaped spreading of peripheral elongated cells forming tube-like structures with increasing complexity over time. |
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