| Name | AT1 |
|---|---|
| Synonyms | AG2S; AT1; AGTR 1; AGTR1; AGTR1A; AGTR1B; AT1AR; AT1B… |
| Name | SMA |
|---|---|
| CAS | sodium 2-chloroacetate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 20232302 | Roson MI, Della Penna SL, Cao G, Gorzalczany S, Pandolfo M, Toblli JE, Fernandez BE: Different protective actions of losartan and tempol on the renal inflammatory response to acute sodium overload. J Cell Physiol. 2010 Mar 15. Sprague-Dawley rats were infused for 2 h with isotonic saline solution (Control group) and with hypertonic saline solution alone (Na group), plus the AT1 receptor antagonist losartan (10 mg kg (-1) in bolus) (Na-Los group), or plus the superoxide dismutase mimetic tempol (0.5 mg min (-1) kg (-1)) (Na-Temp group). |
1(0,0,0,1) | Details |
| 20044807 | Moreno M, Gonzalo T, Kok RJ, Sancho-Bru P, van Beuge M, Swart J, Prakash J, Temming K, Fondevila C, Beljaars L, Lacombe M, van der Hoeven P, Arroyo V, Poelstra K, Brenner DA, Gines P, Bataller R: Reduction of advanced liver fibrosis by short-term targeted delivery of an angiotensin receptor blocker to hepatic stellate cells in rats. Hepatology. 2010 Mar;51(3):942-52. Angiotensin type 1 (AT1) receptor blockers attenuate liver fibrogenesis, yet their efficacy in reversing advanced fibrosis is unknown. |
3(0,0,0,3) | Details |
| 19616542 | Del Prete D, Ceol M, Anglani F, Vianello D, Tiralongo E, Valente M, Graziotto R, Bonfante L, Scaparrotta G, Furian L, Rigotti P, Gambaro G, D'Angelo A: Early activation of fibrogenesis in transplanted kidneys: a study on serial renal biopsies. Exp Mol Pathol. 2009 Oct;87(2):141-5. Epub 2009 Jul 16. Morphometric alpha SMA and TGF beta 1 analysis, and Masson's Trichrome staining were performed. mRNA levels of angiotensinogen, renin, ACE, AT1-R, AT2-R, TGF beta 1, BMP-7, Coll III, fibronectin and alpha SMA were analyzed by real-time RT/PCR. |
2(0,0,0,2) | Details |
| 17959033 | Liu BC, Xia HL, Wu JN, Zhang XL, Liu DG, Gong YX: Influence of irbesartan on expression of ILK and its relationship with epithelial-mesenchymal transition in mice with unilateral ureteral obstruction. Acta Pharmacol Sin. 2007 Nov;28(11):1810-8. AIM: Irbesartan, a new antagonist of the type 1 angiotensin II receptor, has been proven to be renal protective in both diabetic and non-diabetic nephropathy, but its exact mechanism is still uncertain. |
1(0,0,0,1) | Details |
| 20015943 | Yadav A, Vallabu S, Kumar D, Ding G, Charney DN, Chander PN, Singhal PC: HIVAN phenotype: consequence of epithelial mesenchymal transdifferentiation. Am J Physiol Renal Physiol. 2010 Mar;298(3):F734-44. Epub 2009 Dec 16. To evaluate the role of ANG II, Tg26 mice in groups of three were administered either normal saline or telmisartan (an AT1 receptor blocker) for 2 wk, followed by evaluation for renal cell EMT. |
1(0,0,0,1) | Details |